Posted by Bob P (129.65.46.87) on December 21, 2001 at 10:07:53:
In Reply to: Cafergot posted by skylark on December 21, 2001 at 00:10:47:
Unlike the triptans which are selective in constricting the crainial vessels, cafergot will constrict the vessels throughout the entire body. It works well in constricting the vessels for a few hours and also inhibits the neuropeptides for up to 20 hours.
BUT, if you take too much of it or take it for too long it can shut down your circulation and cause gangrene resulting in the loss of finger, toes, etc.
You're not supposed to take more than 10 tablets per week. I've taken up 25 tabs per week resulting in cold toes and fingers. This past cluster I took 2 tabs a day with none of the cold didgets.
Being episodic, I only take it for a couple of months at a time.
Another side fo taking it is rebound headaches.