Posted by Ueli (195.162.175.19) on October 11, 2001 at 19:24:32:
In Reply to: Anyone had success with pushing up Verapamil dosage? posted by Mike on October 11, 2001 at 18:27:33:
Quotes from two articles everybody should read:
From Correct management of cluster headaches by Prof Peter Goadsby and Dr Manjit Matharu:
Verapamil is the preventative drug of choice in both episodic and chronic CH. Clinical experience has demonstrated that higher doses than those used in cardiological indications are needed, so outpatient assessment and follow-up is appropriate. The dose is increased until the cluster attacks are suppressed, side-effects intervene or the maximum dose of 960mg daily is achieved.
From Medscape article: The Treatment of Cluster Headache and Facial Pain
Clinical experience suggests that verapamil is the best prophylactic treatment. However, 800 mg or more may be necessary before patients respond.
(You need a password to access Medscape, but it is available to everybody for free.)
PFNAD,
Ueli