Posted by Ueli (195.162.173.67) on May 08, 2001 at 21:23:26:
In Reply to: Axert posted by Joy on May 08, 2001 at 19:14:11:
Brandon Mitchel Kilgariff is such a beautiful baby, congatulations Devney and grandma Elaine, that I forgive jonny for once for overwriting my post :-)
Here another try:
Almotriptan malate (Axert) was introduced in March in many European countries, under the trade name Almogran.
Up to now, there is not very much about it on the net.
It is a selective 5-HT1B and 5-HT1D receptor agonist, said to be considerably more selective for the cranial vessels than the coronary vessels.
From what I gathered, it is similar to Naratriptan (Amerge / Naramig), a bit faster in action but with slightly more (but still very low) side effects. That price of Almotriptan (in Germany) is similar to other triptan tablets, that is: very high :-(
Its 'kick-in time' is too long to be useful as an CH abortive. But maybe it could be used as a preventative for the night (in the way I use Naratriptan) if its half life time is long enough, but for this I could not find any reference.
Here a few links I found:
First one from CH.com :-) Doug W on Feb 24
A short description: Almirall Prodesfarma
And another one: pharmj.com
Tip: If you want to search for Axert also put Almotriptan and Almogran into the search engine. You get more hits if you can read Spanish, as Almotriptan was developed in Spain :-)