Posted by The other Todd (64.34.202.197) on September 10, 2000 at 22:12:36:
In Reply to: Do you have a chemical or generic name ofr the DHE-45? nt posted by Miguel on September 10, 2000 at 21:51:08:
D.H.E. 45® is ergotamine hydrogenated in the 9, 10 position as the mesylate salt. D.H.E. 45® is known chemically as ergotaman-3',6',18-trione,9,10-dihydro-12'-hydroxy-2'-methyl-5'- (phenylmethyl) (5'a)-, monomethanesulfonate. Its molecular weight is 679. 80 and its empirical formula is C13H37N5O5 · CH4O3S.
D.H.E. 45® (dihydroergotamine mesylate) Injection, USP is a clear, colorless solution supplied in sterile ampuls for I.V., I.M. , or subcutaneous administration containing per mL:
dihydroergotamine mesylate, USP .................................. 1 mg
methanesulfonic acid/sodium hydroxide, qs to ..................pH 3.6 ± 0. 4
alcohol USP ...................................................................6.1 % by vol.
glycerin, UP ...................................................................15% by wt.
water for injection, USP , qs to ...................................... 1 ml .