Posted by Miguel (209.42.192.28) on August 16, 2000 at 01:00:46:
In Reply to: actifed posted by Barbara on August 15, 2000 at 22:10:21:
Actifed is an anti-histaminic agent like no other.
Pseudoephedrine (actifed contains this)
Classification: Direct- and indirect-acting
sympathomimetic (the difference), nasal decongestant
Action/Kinetics: Produces direct stimulation of
both alpha-(pronounced) and beta-adrenergic
receptors, as well as indirect stimulation
through release of norepinephrine from storage
sites. Results in decongestant effect on the
nasal mucosa. Systemic administration
eliminates possible damage to the nasal mucosa.
Onset: 15-30 min. Time to peak effect: 30-60 min.
Duration: 3-4 hr. Extended-release: duration, 8-12 hr.
Urinary excretion slowed by alkalinization,
causing reabsorption of drug.
Uses: Nasal congestion associated with sinus
conditions, otitis, allergies. Relief of
eustachian tube congestion.
Miguel