Posted by Todd (205.188.192.24) on May 18, 2000 at 16:46:30:
In Reply to: Relief at 50,000 fathoms posted by Dennis O'C on May 18, 2000 at 16:40:36:
that the 2 hour 'checkpoint' was selected for some arcane scientific reason. Remember, that's perfectly appropriate for a migraine which might last days.
Nothing in the report indicated one way or the other what the effectiveness is after 10, 15 or 30 minutes, because the study most likely didn't ask that.
I have seen Imitrex injections work in 5 - 10 minutes. I personally experience Imitrex tabs working in 10 minutes. I assume that they work similarly for migrainers, but I can't state that with certainty.
Basically, I read this report to demonstrate that the efficacy of Axert is roughly the same as Imitrex, for migraines. The advantage is the reduced side effects.
And just maybe, with the emergence of Zomig (which seems to show higher efficacy than Imitrex) and Axert, the loss in sales may encourage Glaxo to drop the cost of Imitrex.
We can hope.