With the increased dose you should have a routine EKG to keep an eye on your heart. I assume your doc is aware of this issue.

Timing of the dose is not important because is takes some time before a dose change becomes effective, i.e, it's a slow acting med.
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FYI.
J Headache Pain. 2011 Apr;12(2):173-6. Epub 2011 Jan 22.
Cardiac safety in cluster headache patients using the very high dose of verapamil (=720 mg/day).
Lanteri-Minet M, Silhol F, Piano V, Donnet A.
SourceDépartement d'Evaluation et traitement de la Douleur Médecine palliative, Pôle Neurosciences Cliniques du CHU de Nice, Hôpital Pasteur Avenue de la Voie Romaine, 06002 Nice Cedex, France. lanteri-minet.m@chu-nice.fr

Abstract
Use of high doses of verapamil in preventive treatment of cluster headache (CH) is limited by cardiac toxicity. We systematically assess the cardiac safety of the very high dose of verapamil (verapamil VHD) in CH patients. Our work was a study performed in two French headache centers (Marseilles-Nice) from 12/2005 to 12/2008. CH patients treated with verapamil VHD (=720 mg) were considered with a systematic electrocardiogram (EKG) monitoring. Among 200 CH patients, 29 (14.8%) used verapamil VHD (877±227 mg/day). Incidence of EKG changes was 38% (11/29). Seven (24%) patients presented bradycardia considered as nonserious adverse event (NSAE) and four (14%) patients presented arrhythmia (heart block) considered as serious adverse event (SAE). Patients with EKG changes (1,003±295 mg/day) were taking higher doses than those without EKG changes (800±143 mg/day), but doses were similar in patients with SAE (990±316 mg/day) and those with NSAE (1,011±309 mg/day). Around three-quarters (8/11) of patients presented a delayed-onset cardiac adverse event (delay =2 years). Our work confirms the need for systematic EKG monitoring in CH patients treated with verapamil. Such cardiac safety assessment must be continued even for patients using VHD without any adverse event for a long time.

PMID:21258839[PubMed]
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koctail Hi
            if your taking the d3 regime, with all the co factors ?  including calcium ?   The calcium can effect the verapamil, the trick is to take it 12 hours apart. so because your taking a morning dose and an evening dose of verapamil, I would drop the calcium from the vit d3 regime.
usually its best to take the regime at night with the fattiest meal of the day, but if it includes calcium, that would make your evening dose of verapamil  less effective !!!!
  are you taking every one of the co factors in the regime ?

cheers
col

Hi koctail,
              ive just gone off verapamil, 3 months ago, so im stand alone on the regime,  going thru a cycle at the minute, which im trying to control with increasing the d3 portion.  Hey, I wouldn't stop taking the multi, just take it at night, taking it 12 hours apart and the calcium wont effect the verapamil. but the important co factors in the multi are a must for the d3 absorption,  its turning out that the k2, magnesium d3 and calcium all work so closely together, to get where we need to be.  things like vit a, boron etc etc are also in the multi. If you have to drop the multi, talk to batch about foods that can replace all those necessary elements you'de miss out on.....
good luck with it all
colin

I too would not drop the calcium from the D3 reg,the way I understand it the D3 will find calcium to react with even if it has to deplete it from your bones,I have read material both supporting and denying the claim that Ca will interfere with verapamil efficacy but Im sure if you space them out it shouldnt have any bearing. Ive also read several sources that claim the rapid release verap is more effective than the timed release for CH. I take both,the timed release when Im not very active and the rapid release during the day and evening when Im most active. I felt like the timed release was wearing off during the day but fine for late evening and while Im sleeping,think it may be metabolism. If you read the entire D3 reg as Batch presents it,he describes in detail the roles that the cofactors play and you will understand the importance of taking them all,your mileage may vary but I believe you void your warranty if you dont take the entire regime. The D3 reg is not presented as an ala carte,you need to eat everything on your plate.