Hey Lucifer,
Good question... Vitamin D3 dosing limits are much higher than most think... That said, too much of anything... even water can be harmful...
The good news is there's not been a death attributed to vitamin D3 overdose in recorded medical history... (You can't say that for verapamil)
There's a good reason for this safety record... As the body generates vitamin D3 in the skin when exposed to the UVB in sunlight... it also has built-in mechanisms for regulating its production and serum levels...
What you're looking for is a sum of dose and duration of dose over time to arrive at safe dosing limits... The following chart illustrates safe dosing limits as developed by experts in vitamin D3 therapy. You can find this chart and many others at vitaminDwiki.
See: Multimedia File Viewing and Clickable Links are available for Registered Members only!! You need to
or
Multimedia File Viewing and Clickable Links are available for Registered Members only!! You need to
or
As you can see there's no problem with vitamin D3 doses of 100,000 IU... You just can't take that dose for more than two weeks and a couple days... You'll need to drop down to a vitamin D3 intake of 10,000 to 15,000 IU/day to arrive at a safe dose you can take indefinitely...
My wife has been taking 15,000 IU/day for over two years and loves it... She feels great, looks younger and has more energy than I've seen in 20 years... In short... no problems and her 25(OH)D is around 95-105 ng/mL. She also kicked the heck out of 75 last Christmas... Go figure...
Safe vitamin D3 dosing limits also depend on your present 25(OH)D serum concentration...
In reality, it's your 25(OH)D serum concentration that counts so you take as much vitamin D3 as needed to arrive at the desired 25(OH)D serum concentration. The following chart illustrates the 25(OH)D time course response to various vitamin D3 doses
Multimedia File Viewing and Clickable Links are available for Registered Members only!! You need to
or
For example, based on data collected from here at CH.com and an online survey of CH'ers using the Anti-Inflammatory Regimen, CH'ers need a 25(OH)D serum concentration between 60 and 110 ng/mL in order to experience a therapeutic response... i.e., going pain free... This requires a vitamin D3 dose of 10,000 IU/day which results in a 25(OH)D equilibrium of 85 ng/mL after 4 to 5 months time...
Hope this helps.
Take care and please keep us posted.
V/R, Batch