It is with great disappointment that I am going to give up on the Depakote and Topamax as the Depakote proved to be to much and just knocked the tar out of me. I was taking 1500mg daily along with 400mg daily of Topamax but had taken the Topamax for about a year on its own without good results.
At this point I think I am going to detox my system and treat my CH with an abortive approach using Oxygen and energy drinks. After detox I am going to give vitamin D3 a shot and see how that works.
That is the plan at this moment anyway?.....Johnny

After Topamax, Lithium, Verapamil, Neuronton and cymbalta <--- i know thats a wierd one failed and i couldnt take triptains, I was having over 30 CH a month for yearssss ! Chronic fpr yearssss ! i finally can control. i am on no prevenatives but i can control and that is cutting down on  my attacks. I use Nasal Lidocain spray 2% 2 sprays on side where i have pain, zofran, 1mg Xanax (helps calm me down being i feel like im being stabbed) and then while waiting for Xanax to kick in i have the numbing already in effect i start my oxygen. if i cannot get it under control with the oxygen after 15 -20 and im at a 7+in pain i take a 2mg dilaudid very rarely though. i cannot take triptains. I think a anti-anxiety may help alot of people. i think me going into panic mode during the begging of my CH attacks would make them worse and longer.

Sorry to hear the latest treatment plan tanked... just a few more drugs you can take off the list now. If you get tired of the pharma, or you get to the end of the list with no results... check out clusterbusters.com

I had the same nasty experience with Depakote. Never did a damn thing for me, and I felt like I actually got more headaches when on that stuff. Things improved rapidly after I kicked it to the curb.