I have low T so started getting shots every 3 weeks. I found that the CCH got much worse at the peak plasma level point, then got a bit better until the next shot. My urologist put me on Androgel so that I could better titrate dosage. After a couple of years, I can say for sure that, in my case TRT of any kind leads to the worst CH with 6 or 7 attacks per day. If I stop taking any testosterone, I get one, maybe two or three, but always at night and not as hard to abort

Reading up on TRT and CH I find that many of us are having the opposite experience, where replacement therapy is effective in reducing or eliminating attacks.

Does anyone have any insights about what is going on here?  BTW, I'm chronic 23 years, and definitely NOT a newbie.

I've taken Andrgel too.  It was fairly neutral, neither making things better or worse.  However, I did come off of the andrgel and have NOT had any hits at all.

Thanks to everyone for your replies. Bob P, great to hear from you. I'm going to visit with a new neurologist and headache specialist on Friday and plan to discuss Possible endocrine disorders. About six months before the chronic cluster headaches started, I suffered a skull fracture. This is never been considered to be a factor in the origin of the cluster headaches, but with the new focus on traumatic brain injury, I think it's worth another look.