Hey PedroPedro,

Sorry you're back to see us, but a lot has happened since you were last here...

We've found that nearly all of us CH'ers are vitamin D3 deficient and that deficiency is contributing to our CH... 

Most episodic CH'ers with active CH who have the test for 25(OH)D, a metabolite of vitamin D3, have results below 30 ng/mL...  Some chronic CH'ers with active CH have tested as high as 55 to 63 ng/mL.

The good news is CH'ers who go pain free on the anti-inflammatory regimen with 10,000 IU/day vitamin D3 have serum concentrations of 25(OH)D in a range from 60-110 ng/mL...  so it's clear a higher concentration of 25(OH)D correlates with a lower incidence of CH attacks.

The present success rate for this method of preventing cluster headache is 75%.  To date 105 out of the 140 CH'ers who posted they've started this regimen have gone pain free in less than three weeks or had a significant reduction in the frequency and severity of their CH..

The other good news is this regimen works well with traditional standards of care preventatives for CH.

I've updated the anti-inflammatory regimen with additional magnesium and added vitamin A as shown below.  The main reason for this update is to help the other 25% of CH'ers who didn't respond to this regimen as rapidly as the others.

Once you get your 25(OH)D serum concentration into the green zone (60-110 ng/mL) and go pain free.  You should be able to lower the vitamin D3 dose to 75 IU/Kg/day.  For most of us that works out somewhere between 5000 to 10,000 IU/day

The new suggested anti-inflammatory regimen supplements and dosage includes:

10,000 IU/day Vitamin D3
  2,000 mg/day Omega 3 Fish Oil
  5,000 500 mg/day Calcium (calcium citrate preferred)

In order to receive the most health benefit from increased levels of vitamin D3, the proper cofactors must be present in the body. Vitamin D3 has many cofactors, but the ones listed below are the most important. Magnesium should be considered the most important one of all.

Magnesium   400 mg/day  (liquid softgels, magnesium
                   citrate or magnesium gluconate preferred)

Vitamin K2    120 mcg/day - Men, 90 mcg/day - Women

Vitamin A      900 mcg (3,000 IU) for men and
                    700 mcg (2,333 IU) for women

Zinc               10 mg/day

Boron              1 mg/day

You can read about the vitamin D3 cofactors at the following link: Multimedia File Viewing and Clickable Links are available for Registered Members only!!  You need to or

With the exception of vitamin D3 dose which is higher than the Institute of Medicine suggests, all the other supplements and dosages listed in this regimen are at or below the recommended dietary allowance (RDA).

Take care and please keep us posted.

V/R, Batch