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lennycohen CH.com Junior Offline Posts: 61 Clemmons, NC Gender:	Mixing Triptans Jun 24^th, 2010 at 11:29pm What's so bad about mixing triptans? Couldn't you take a Frova to stave off a night attack and use Trex injector or oxygen if it breaks thru?
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Racer1_NC CH.com Moderator CH.com Alumnus Offline "Well, let's go see." Posts: 4417 Lewisville, NC Gender:	Re: Mixing Triptans Reply #1 - Jun 25^th, 2010 at 12:46am lennycohen wrote on Jun 24^th, 2010 at 11:29pm: What's so bad about mixing triptans? Couldn't you take a Frova to stave off a night attack and use Trex injector or oxygen if it breaks thru? Oxygen is OK. Use of different triptans in a 24 hour period can result in serious complications.
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Callico CH.com Hall of Famer Offline Author of "Stranded at Romson's Lodge Posts: 4916 Aurora IL Gender:	Re: Mixing Triptans Reply #2 - Jun 25^th, 2010 at 1:26am It depends on how badly you want to live. Jerry
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Brew CH.com Sponsor CH.com Alumnus Offline Posts: 14163	Re: Mixing Triptans Reply #3 - Jun 25^th, 2010 at 6:45am It should not be done without express consent of your supervising doctor, and I think your doc would want to do a cardio work-up on you first. To make sure your ol' ticker can handle it.
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Karla CH.com Alumnus Offline One of Many and Never Alone - Join OUCH Posts: 3837 x1\|Madison WI USA Gender:	Re: Mixing Triptans Reply #4 - Jun 25^th, 2010 at 11:25am You are treading on thin ice so to speak. It is very complex but the heart usually just can not handle it. It says in the insert that you are not to mix them. Please talk to your dr about this before you proceed to do it again. We want you around for awhile.
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Brew

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Re: Mixing Triptans
Reply #5 - Jun 25^th, 2010 at 11:35am

Make no mistake - a healthy heart CAN handle it, but which kinds and how much should be something you AND your doctor discuss before doing it.

I'm living proof that it can work, and work well. My neuro had me on a prophylactic dose of Amerge for several months while using Maxalt when needed for breakthrough attacks. But you must insist on a thorough cardiac work-up first.

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"I have been asked if I have changed in these past 25 years. No, I am the same. Only more so." --Ayn Rand

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lennycohen CH.com Junior Offline Posts: 61 Clemmons, NC Gender:	Re: Mixing Triptans Reply #6 - Jun 25^th, 2010 at 2:19pm Thanks for the replies - I actually haven't tried it yet, but I'm trying to think of all the options, I'm back up to 3-4 kip 7+ / day ---- started lithium this morning ---
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Trooper CH.com Veteran Offline I ain't skeert! Posts: 115 x0\|mckinney\|USA\|\|0\|0\|TX,Texas Gender:	Re: Mixing Triptans Reply #7 - Jun 25^th, 2010 at 10:46pm It seems like I remember several years ago that we had a member that actually had a stroke from doing this. I was very new to the board at the time but I do remember reading something about it. Maybe some of the veterans around here could chime in on this subject.
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Lettucehead

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Re: Mixing Triptans
Reply #8 - Jun 27^th, 2010 at 12:12am

ok, my initial reaction from reading this thread was 'AHHHHHHH!! AHHHHHH!!!'

But on further reflection, I'm thinking it would depend on your cardiac risk factors (age, diabetes, smoking, hypertension, etc.) and how much total triptan you're taking.

Essentially, you have to make sure not to go over a total triptan dose maximum - i.e. imitrex oral is 200mg/d max - if you took an oral tab of 100mg and later an inj, I'm thinking then you would reach your daily max, but not necessarily over it - this may still hold true even with cross scripts of tripans. still scary though...

Please, make sure you get a cardiac work-up - EKG and discussion of risks at the very least and I would actually recommend a stress test - insurance would likely cover it under a diagnosis of 'starting high cardiac risk medications'

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Listen, and understand. That terminator is out there. It can't be bargained with. It can't be reasoned with. It doesn't feel pity, or remorse, or fear... 'The Terminator' AKA CH

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MJ CH.com Hall of Famer Offline Posts: 1205 x1\|\|USA\|usa\|299\|85\|MN Gender:	Re: Mixing Triptans Reply #9 - Jul 3^rd, 2010 at 2:45am There are a lot of cases of mixing triptans for various results in the medical literature but the largest issue is the possibility of serotonin syndrome, which can cause serious issues and death. Multimedia File Viewing and Clickable Links are available for Registered Members only!! You need to or
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Brew CH.com Sponsor CH.com Alumnus Offline Posts: 14163	Re: Mixing Triptans Reply #10 - Jul 3^rd, 2010 at 9:58am MJ wrote on Jul 3^rd, 2010 at 2:45am: ...which can cause serious issues and death. Yeah, I'd say that's kind of a serious issue.
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black

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Re: Mixing Triptans
Reply #11 - Jul 3^rd, 2010 at 4:00pm

i am using dihydergot tablets.
if you having a bad time you might consider this option too by maybe switching with it at least for a while.
it doesn't give me any rebound headaches as imigran
i think it has longer effect and in bad periods of year
can take up to three tablets with only side effect
a sort of tiredness in hands and legs.
Maybe it could work along with a coffee or energy drink at least for a while as you haven't get used to it?
just an option but you know how these work.
always discussing first with a neuro. Wink

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Oh come on!it's just water.It can't be that bad!

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black CH.com Old Timer Offline I Love CH.com! Posts: 347 Greece,Athens Gender:	Re: Mixing Triptans Reply #12 - Jul 5^th, 2010 at 1:38pm Quote: can take up to three tablets in 24 hours period!not all together sorry for my language
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lennycohen CH.com Junior Offline Posts: 61 Clemmons, NC Gender:	Re: Mixing Triptans Reply #13 - Jul 9^th, 2010 at 7:22am Thanks for all the input. 600 mgs of lithium/day has knocked it down considerably, been on for 12+ days, went from a constant 3-4 with excursions to 8, to a constant 1-2, with about a 1x/day excursion to 4 -- haven't used Imitrex inj or Sumavel for more than a week - we'll see how long this episode goes.
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bejeeber

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Re: Mixing Triptans
Reply #14 - Jul 9^th, 2010 at 1:35pm

Great to hear that the liithium is working for ya like that Lenny.

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CH according to Bejeeber:

Strictly relying on doctors for CH treatment is often a prescription that will keep you in a whole lot of PAIN. Doctors are WAY behind in many respects, and they are usually completely unaware of the benefits of high flow 100% O2.

There are lots of effective treatments documented at this site. Take matters into your own hands, learn as much as you can here and at clusterbusters.com, put it into practice, then tell this CH beast Jeebs said hello right before you bash him so hard with a swift uppercut knockout punch that his stupid horns go flinging right off.

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Guiseppi

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Re: Mixing Triptans
Reply #15 - Jul 9^th, 2010 at 1:51pm

Lithium has been my best freind for many many years. I go at 1200 mg a day and it blocks up to 60-70% of my attacks. Used to use 900 but over the years it became ineffective at that level.

At 1200 mg even my wife doesn't notice any difference so if you end up having to increase don't sweat it. Damned glad you're getting relief that's great news.

Joe

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"Somebody had to say it" is usually a piss poor excuse to be mean.

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Lettucehead CH.com Old Timer Offline I am very blessed... Posts: 293 Iowa Gender:	Re: Mixing Triptans Reply #16 - Jul 9^th, 2010 at 10:29pm oh, hooray!!!
Back to top	Listen, and understand. That terminator is out there. It can't be bargained with. It can't be reasoned with. It doesn't feel pity, or remorse, or fear... 'The Terminator' AKA CH IP Logged

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