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New CH.com Forum › Cluster Headache Help and Support › Medications, Treatments, Therapies › Cyproheptadine / Periactin

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Cyproheptadine / Periactin (Read 1267 times)

monty

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The Swamp, Florida

Cyproheptadine / Periactin
May 5^th, 2010 at 6:29pm

Was just looking up cyproheptadine (which my cat got a script for) - looks like it might be a good preventive med for clusters.

"Cyproheptadine is an antihistaminic/anticholinergic and antiserotonergic agent. It acts as a 5-HT2 receptor antagonist as well and also blocks calcium channels."

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The outer boundary of what we currently believe is feasible is far short of what we actually must do.

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Guiseppi CH.com Moderator CH.com Alumnus Offline San Diego to Florida 05-16-2011 Posts: 12063 SAN DIEGO, CALIFORNIA USA Gender:	Re: Cyproheptadine / Periactin Reply #1 - May 5^th, 2010 at 7:02pm One of it's already listed uses is preventing migrains.....damn....who'd of thought you could learn stuff from a cat! Joe
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jon019 CH.com Alumnus Offline "Ya gotta believe!" Posts: 1656 USA Gender:	Re: Cyproheptadine / Periactin Reply #2 - May 5^th, 2010 at 8:29pm Does sound good...and makes sense it is a migraine drug. During my early ch career that type was all I was ever prescribed (is it any different now?). My Docs used to run from the exam office to read up on what they knew nothing about. It's been 20 yrs or so since I tried Periactin. Did nothing for me...YMMV. Best, Jon
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MJ CH.com Hall of Famer Offline Posts: 1205 x1\|\|USA\|usa\|299\|85\|MN Gender:	Re: Cyproheptadine / Periactin Reply #3 - May 5^th, 2010 at 10:29pm Periactin / Cyproheptadine, like Jon, was one of the first meds I was given back maybe 30 years ago. May have helped a little in the early days before things got rough. Back when CH was sometimes refered to as histamine headaches.
Back to top	« Last Edit: May 5^th, 2010 at 10:32pm by MJ » MJ IP Logged

George CH.com Moderator CH.com Alumnus Offline Black-Billed Magpie Posts: 8126 Boise, Idaho USA Gender:	Re: Cyproheptadine / Periactin Reply #4 - May 6^th, 2010 at 1:19am I was prescribed Periactin during the course of two separate CH cycles when I was first diagnosed. (late sixties, perhaps 1970 or so). Did nothing at all, as far as I could tell--good, bad, or indifferent. Your mileage, of course, may vary. Best, George
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