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New CH.com Forum › Cluster Headache Help and Support › Medications, Treatments, Therapies › Calcium channel blocker

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Calcium channel blocker (Read 2126 times)

LasVegas CH.com Sponsor Offline Episodic CH since 11 yrs old, now 50. Posts: 2020 north of the 60th parallel Gender:	Calcium channel blocker Mar 20^th, 2010 at 11:18pm Since Verapamil is a calcium channel blocker, curious if bone loss is common?
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Brew CH.com Sponsor CH.com Alumnus Offline Posts: 14163	Re: Calcium channel blocker Reply #1 - Mar 20^th, 2010 at 11:35pm It sure makes me lose a bone.
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LasVegas CH.com Sponsor Offline Episodic CH since 11 yrs old, now 50. Posts: 2020 north of the 60th parallel Gender:	Re: Calcium channel blocker Reply #2 - Mar 20^th, 2010 at 11:44pm that was funny Brew, thanks for the laugh, but seriously curious if anybody has noted jaw bone loss and losing teeth or some other type of bone loss as side effect
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Brew CH.com Sponsor CH.com Alumnus Offline Posts: 14163	Re: Calcium channel blocker Reply #3 - Mar 20^th, 2010 at 11:46pm It's not funny at all. That's why I don't take it anymore.
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LasVegas CH.com Sponsor Offline Episodic CH since 11 yrs old, now 50. Posts: 2020 north of the 60th parallel Gender:	Re: Calcium channel blocker Reply #4 - Mar 20^th, 2010 at 11:49pm Brew, thought you were expressing a male gendered sarcastic remark, so with all due respect, my apologies for misunderstanding your comment. So you have had bone loss attributed to Verapamil, how so?
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Bob Johnson

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Re: Calcium channel blocker
Reply #5 - Mar 21^st, 2010 at 11:04am

"Verapamil does not alter total serum calcium levels. However, one report has suggested that calcium levels above the normal range may alter the therapeutic effect of verapamil."
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It influences the movement of chemicals in/out of certain types of cells but doesn't affect our bones.

Bob Johnson

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deltadarlin

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Re: Calcium channel blocker
Reply #6 - Mar 21^st, 2010 at 11:07am

From what I've read, Calcium Channel blockers don't block calcium from being absorbed via the gut into the bloodstream.

Mechanism of Action
Inhibit passage of calcium through the voltage gated L-type (for Large/Long-lasting current) calcium channel on vascular smooth muscle cells and cardiac myocytes, reducing calcium availability for muscle contraction.

Calcium channel antagonists block the inward movement of calcium by binding to the L-type calcium channels in the heart and in smooth muscle of the peripheral vasculature. CCB’s dilate coronary arteries and peripheral arterioles, but not veins.

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Brew

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Re: Calcium channel blocker
Reply #7 - Mar 21^st, 2010 at 11:42am

LasVegas wrote on Mar 20^th, 2010 at 11:49pm:

Brew, thought you were expressing a male gendered sarcastic remark, so with all due respect, my apologies for misunderstanding your comment. So you have had bone loss attributed to Verapamil, how so?

"Male gendered," yes. "Sarcastic," no.

Humorous, I had hoped.

It's still the main reason I won't take it anymore.

"I have been asked if I have changed in these past 25 years. No, I am the same. Only more so." --Ayn Rand

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Marc Ex Member Gender:	Re: Calcium channel blocker Reply #8 - Mar 22^nd, 2010 at 8:33pm Brew wrote on Mar 20^th, 2010 at 11:35pm: It sure makes me lose a bone. I'm still rolling on the floor laughing
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