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Bromo Trials... anyone got info? (Read 1532 times)
FramCire
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Bromo Trials... anyone got info?
Nov 5th, 2009 at 9:50pm
 
NG Explorer said there are no trials on 2-Bromo currently planned.  Could anyone give me as much info on the initial trial and what is underway?  I have a contact in the pharmaceutical industry who I was talking to who was interested in this information.

Before anyone gets their hopes up, this contact is not a decision maker and thus there is very little , if any, chance that this will turn into anything, but I figured it was just gathering some info so why not.

I repeat, I am fairly sure this won't spark anything, but hey........ even if it was a janitor.... I'd do it.
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You've overstayed your welcome since the day we met but it doesn't seem to matter to you.  No medications are your master, nothing makes you fret, it's a helpless feeling having nothing I can do
 
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Brew
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Re: Bromo Trials... anyone got info?
Reply #1 - Nov 5th, 2009 at 10:08pm
 
I thought I heard a certain person at the Chicago CB conference say that they were working on getting trials going at Harvard, possibly as early as next year.
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Callico
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Re: Bromo Trials... anyone got info?
Reply #2 - Nov 6th, 2009 at 6:43pm
 
Bob Wold would be the one to know about it.  If you don't hear from him here try contacting him through the new Clusterbusters message board.

Jerry
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"Political correctness is a doctrine, fostered by a delusional, illogical minority, and rabidly promoted by an unscrupulous mainstream media, which holds forth the proposition that it is entirely possible to pick up a piece of dung by the clean end." Texas A&M Student (unknown)
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FramCire
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Re: Bromo Trials... anyone got info?
Reply #3 - Nov 7th, 2009 at 5:31pm
 
I'll try to get a hold of him.  For as long as I have been here, you would think I would have known to talk to him.

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You've overstayed your welcome since the day we met but it doesn't seem to matter to you.  No medications are your master, nothing makes you fret, it's a helpless feeling having nothing I can do
 
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Val_
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Re: Bromo Trials... anyone got info?
Reply #4 - Nov 8th, 2009 at 11:50pm
 
Funny, I was given an article about this by a doc last month!  I told him about the special on Nat'l Geo last week  Wink
There was a Very short article published in Cephalalgia titled "Attack Cessation and remission induction with 2-bromo-LSD for cluster headache".  John Halpern of Harvard apparently had a clinical case with 4 case study participants (oooohhh I know the thorough nature of it) - but it is considered an open-label trial at this point anyway.  I guess Halpern would be the person to get in touch with Eric...
As far as the trial, one person had a 30% reduction in pain intensity and 73% reduction in frequency (after 2 months) for a period of 4 months, while the other 3 participants had complete or "near complete" remission of symptoms for at least 2 months after treatment!  WOOT now That's What I'm talking About!  If you get in touch with Halpern and he has room for more CCH participants, I might be interesting in moving to MA.   Grin
(One more interesting fact - these 4 participants were outpatient in Hannover, Germany actually.  They only had 3 treatments of BOL, or 2-bromo-LSD, and the treatments were separated by 5 days.)

Val
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val2651  
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Re: Bromo Trials... anyone got info?
Reply #5 - Nov 9th, 2009 at 7:22am
 
Val_ wrote on Nov 8th, 2009 at 11:50pm:
Funny, I was given an article about this by a doc last month!  I told him about the special on Nat'l Geo last week  Wink
There was a Very short article published in Cephalalgia titled "Attack Cessation and remission induction with 2-bromo-LSD for cluster headache".  John Halpern of Harvard apparently had a clinical case with 4 case study participants (oooohhh I know the thorough nature of it) - but it is considered an open-label trial at this point anyway.  I guess Halpern would be the person to get in touch with Eric...
As far as the trial, one person had a 30% reduction in pain intensity and 73% reduction in frequency (after 2 months) for a period of 4 months, while the other 3 participants had complete or "near complete" remission of symptoms for at least 2 months after treatment!  WOOT now That's What I'm talking About!  If you get in touch with Halpern and he has room for more CCH participants, I might be interesting in moving to MA.   Grin
(One more interesting fact - these 4 participants were outpatient in Hannover, Germany actually.  They only had 3 treatments of BOL, or 2-bromo-LSD, and the treatments were separated by 5 days.)

Val

Dr. Halpern was the "certain person" I was talking about.
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gizmo
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Re: Bromo Trials... anyone got info?
Reply #6 - Nov 9th, 2009 at 10:18am
 
Val_ wrote on Nov 8th, 2009 at 11:50pm:
while the other 3 participants had complete or "near complete" remission of symptoms for at least 2 months after treatment!


For at least two of them (I was one of these lucky guys) the complete or "near complete" remission of symptoms stretched to 6 months.
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FramCire
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Re: Bromo Trials... anyone got info?
Reply #7 - Nov 9th, 2009 at 2:41pm
 
Thanks all.  I have forwarded a preliminary email with some information I got from a person here.  I don't expect much to come of it but you never know.

Crazier things have happened.
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You've overstayed your welcome since the day we met but it doesn't seem to matter to you.  No medications are your master, nothing makes you fret, it's a helpless feeling having nothing I can do
 
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Callico
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Re: Bromo Trials... anyone got info?
Reply #8 - Nov 9th, 2009 at 5:10pm
 
Right now the holdup is the funding to be able to conduct a study in the States as soon as FDA approval is received.  There is no point in applying though without the funding to do the study.  For a mere half mil I'm sure Dr Halpern would be happy to name the study for you.

Jerry
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"Political correctness is a doctrine, fostered by a delusional, illogical minority, and rabidly promoted by an unscrupulous mainstream media, which holds forth the proposition that it is entirely possible to pick up a piece of dung by the clean end." Texas A&M Student (unknown)
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