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Cluster Headache Help and Support >> Cluster Headache Specific >> Family histories.
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Message started by Lucifer on Mar 21st, 2013 at 7:17pm

Title: Family histories.
Post by Lucifer on Mar 21st, 2013 at 7:17pm
Does anyone have family members that suffer from CH? My father gets them chronically, but I am getting conflicting information regarding a genetic predisposition. 

We also get very similar symptoms, except his are chronic. I was just curious if this was common.

Title: Re: Family histories.
Post by Chuh on Mar 21st, 2013 at 9:10pm
Yeah, that can happen (conflicting information)


"Cluster Headache in the United States of America:
Demographics, Clinical Characteristics, Triggers, Suicidality,
and Personal Burden*"

Family History of Cluster Headache.—Of the surveyed
patients, 82% denied a family history of cluster
headache. Of those with a positive family history, a
first-degree relative was noted in 17%, with fathers
being the most commonly cited relative in 6%, while
mothers were noted to have cluster headache in 3%.

Headache
© 2011 American Headache Society Published byWiley Periodicals, Inc.
ISSN 0017-8748
doi: 10.1111/j.1526-4610.2011.02028.x


There are some other publications that indicate genetics are indeed a determining factor:

Orphanet Journal of Rare Diseases 2008, 3:20 doi:10.1186/1750-1172-3-20
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"Cluster Headache"

Initially, CH was not thought to be a genetic disease. With
official criteria published and the increasing recognition
of the disease, a genetic aspect of CH has been identified.
Cases of twin pairs affected by CH have been published
[30-32]. Studies using large twin registries have shown
that monozygotic twins present a higher concordance rate
for CH (2/12 pairs) than dizygotic twins (0/25 pairs),
indicating the existence of genetic factors, but monozygotic
twins can also be concordant or discordant for CH,
confirming a role for environmental factors [11,33]. Family
studies of CH patients' cohorts have shown a familial
aggregation in 7% to 20% of patients, and a relative risk
for first-degree relatives between 14 and 39 [34-36].

Orphanet Journal of Rare Diseases 2008, 3:20 doi:10.1186/1750-1172-3-20
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It comes down to how you decide to interpret the data. Just because it's plastered all over the place don't make it true...


Peace Of Mind

Title: Re: Family histories.
Post by Guiseppi on Mar 24th, 2013 at 8:50am
I have a large extended family, 13 siblings, closing in on 200 with children, nieces nephews, great nieces and nephews and so far I'm the only one with the black straw.

Joe

Title: Re: Family histories.
Post by Sledge007 on Mar 24th, 2013 at 10:06am
My mom and her dad both had cluster headaches. Both of them eventually grew out of them sometime in their 40s. I'm hoping for the same. I have two brothers and a sister that don't have them, but I am also the oldest, so it's possible they might but haven't started yet.

Title: Re: Family histories.
Post by jess-MTL on Mar 25th, 2013 at 9:39am
No, CH were unheard of before me!
My dad had major sinus problems, so we thought I had sinus headaches in the beginning. I didn't know any better, I had never had any problems before. He had told me that hot water helped him, so trying to "cure" mine, I burnt my face with the hottest water possible. Turns out, it didn't help, and I didn't have a sinus problem either.

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