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Message started by FramCire on Nov 5th, 2009 at 9:50pm

Title: Bromo Trials... anyone got info?
Post by FramCire on Nov 5th, 2009 at 9:50pm
NG Explorer said there are no trials on 2-Bromo currently planned.  Could anyone give me as much info on the initial trial and what is underway?  I have a contact in the pharmaceutical industry who I was talking to who was interested in this information.

Before anyone gets their hopes up, this contact is not a decision maker and thus there is very little , if any, chance that this will turn into anything, but I figured it was just gathering some info so why not.

I repeat, I am fairly sure this won't spark anything, but hey........ even if it was a janitor.... I'd do it.

Title: Re: Bromo Trials... anyone got info?
Post by Brew on Nov 5th, 2009 at 10:08pm
I thought I heard a certain person at the Chicago CB conference say that they were working on getting trials going at Harvard, possibly as early as next year.

Title: Re: Bromo Trials... anyone got info?
Post by Callico on Nov 6th, 2009 at 6:43pm
Bob Wold would be the one to know about it.  If you don't hear from him here try contacting him through the new Clusterbusters message board.

Jerry

Title: Re: Bromo Trials... anyone got info?
Post by FramCire on Nov 7th, 2009 at 5:31pm
I'll try to get a hold of him.  For as long as I have been here, you would think I would have known to talk to him.


Title: Re: Bromo Trials... anyone got info?
Post by Val_ on Nov 8th, 2009 at 11:50pm
Funny, I was given an article about this by a doc last month!  I told him about the special on Nat'l Geo last week  ;)
There was a Very short article published in Cephalalgia titled "Attack Cessation and remission induction with 2-bromo-LSD for cluster headache".  John Halpern of Harvard apparently had a clinical case with 4 case study participants (oooohhh I know the thorough nature of it) - but it is considered an open-label trial at this point anyway.  I guess Halpern would be the person to get in touch with Eric...
As far as the trial, one person had a 30% reduction in pain intensity and 73% reduction in frequency (after 2 months) for a period of 4 months, while the other 3 participants had complete or "near complete" remission of symptoms for at least 2 months after treatment!  WOOT now That's What I'm talking About!  If you get in touch with Halpern and he has room for more CCH participants, I might be interesting in moving to MA.   ;D
(One more interesting fact - these 4 participants were outpatient in Hannover, Germany actually.  They only had 3 treatments of BOL, or 2-bromo-LSD, and the treatments were separated by 5 days.)

Val

Title: Re: Bromo Trials... anyone got info?
Post by Brew on Nov 9th, 2009 at 7:22am

Val_ wrote on Nov 8th, 2009 at 11:50pm:
Funny, I was given an article about this by a doc last month!  I told him about the special on Nat'l Geo last week  ;)
There was a Very short article published in Cephalalgia titled "Attack Cessation and remission induction with 2-bromo-LSD for cluster headache".  John Halpern of Harvard apparently had a clinical case with 4 case study participants (oooohhh I know the thorough nature of it) - but it is considered an open-label trial at this point anyway.  I guess Halpern would be the person to get in touch with Eric...
As far as the trial, one person had a 30% reduction in pain intensity and 73% reduction in frequency (after 2 months) for a period of 4 months, while the other 3 participants had complete or "near complete" remission of symptoms for at least 2 months after treatment!  WOOT now That's What I'm talking About!  If you get in touch with Halpern and he has room for more CCH participants, I might be interesting in moving to MA.   ;D
(One more interesting fact - these 4 participants were outpatient in Hannover, Germany actually.  They only had 3 treatments of BOL, or 2-bromo-LSD, and the treatments were separated by 5 days.)

Val

Dr. Halpern was the "certain person" I was talking about.

Title: Re: Bromo Trials... anyone got info?
Post by gizmo on Nov 9th, 2009 at 10:18am

Val_ wrote on Nov 8th, 2009 at 11:50pm:
while the other 3 participants had complete or "near complete" remission of symptoms for at least 2 months after treatment!


For at least two of them (I was one of these lucky guys) the complete or "near complete" remission of symptoms stretched to 6 months.

Title: Re: Bromo Trials... anyone got info?
Post by FramCire on Nov 9th, 2009 at 2:41pm
Thanks all.  I have forwarded a preliminary email with some information I got from a person here.  I don't expect much to come of it but you never know.

Crazier things have happened.

Title: Re: Bromo Trials... anyone got info?
Post by Callico on Nov 9th, 2009 at 5:10pm
Right now the holdup is the funding to be able to conduct a study in the States as soon as FDA approval is received.  There is no point in applying though without the funding to do the study.  For a mere half mil I'm sure Dr Halpern would be happy to name the study for you.

Jerry

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