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Cluster Headache Help and Support >> Medications,  Treatments,  Therapies >> Whacky question
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Message started by seaworthy on Sep 21st, 2009 at 7:14pm

Title: Whacky question
Post by seaworthy on Sep 21st, 2009 at 7:14pm
But what better place to ask it?

Is the liquid imitrex in the inhalers the same as the liquid imitrex in the vials?

Title: Re: Whacky question
Post by Brew on Sep 21st, 2009 at 9:21pm
I think the difference in the actual amount of sumatriptan in the different applications is because of the way it gets absorbed into the system. It's the same drug in all three forms (injectable, inhaled, and oral).

Not sure what the difference is in the other things included in each of the three forms.

Title: Re: Whacky question
Post by Ginger S. on Sep 21st, 2009 at 9:32pm
Same Drug different absorption methods and dosages as Brew said.  Slowest absorption is the pill, after that is the nasal and the fastest of course is the shot.

I don't recommend injecting the nasal Imitrex though or chopping up pills and snorting them or any other non prescribed form of taking the Imitrex.  :)

Title: Re: Whacky question
Post by seaworthy on Sep 21st, 2009 at 9:52pm
thats what I was getting at. Can the imitrex in the inhaler be drawn out for injection?

The inhaler indicates 20 mg. A vial is 6 mg.

Can the inhaler contents be broken down into 3 parts for injection?

For me that would equal 6 injections a I only use 3 mg at a time.

Title: Re: Whacky question
Post by bejeeber on Sep 21st, 2009 at 10:02pm

seaworthy wrote on Sep 21st, 2009 at 9:52pm:
Can the inhaler contents be broken down into 3 parts for injection?


Now THATS working the system!

I would be concerned that it could be a different formulation or something?? Hmmm come to think of it though, probably not?



Title: Re: Whacky question
Post by seaworthy on Sep 21st, 2009 at 10:11pm

Quote:
I would be concerned that it could be a different formulation or something??


Thats my only concern. This idea is really no crazier than when the imitrex tip of breaking down the auto injector EXCEPT for the question of formular.

I may be a guinee pig. If you never see another post from me again then the answer is "no you cant do it".  :-/

Title: Re: Whacky question
Post by Brew on Sep 21st, 2009 at 10:29pm
Can I have your dog?

Title: Re: Whacky question
Post by seaworthy on Sep 21st, 2009 at 10:34pm
You can have this whiney ass mutt one way or the other.

I'll Fedex him to you tomorrow

Title: Re: Whacky question
Post by Brew on Sep 21st, 2009 at 10:50pm
;D

Title: Re: Whacky question
Post by seaworthy on Sep 21st, 2009 at 11:03pm
I think I'll wait for a little more input on this.

The imitrex I mean.

Your getting the dog.

Title: Re: Whacky question
Post by bejeeber on Sep 22nd, 2009 at 12:27am
There probably is something somewhere online wouldntcha think that lists exactly what is contained in both the injection and the spray?

Wish I didn't have to bail right now or I'd attempt a search for it myself.




Title: Re: Whacky question
Post by bejeeber on Sep 22nd, 2009 at 2:37am
Came back, went hunting, found this at /START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!!  You need to Login or RegisterEND PRINTPAGE:

IMITREX Injection is a clear, colorless to pale yellow, sterile, nonpyrogenic solution for
subcutaneous injection. Each 0.5 mL of IMITREX Injection 8 mg/mL solution contains 4 mg of
sumatriptan (base) as the succinate salt and 3.8 mg of sodium chloride, USP in Water for
Injection, USP. Each 0.5 mL of IMITREX Injection 12 mg/mL solution contains 6 mg of
sumatriptan (base) as the succinate salt and 3.5 mg of sodium chloride, USP in Water for
Injection, USP. The pH range of both solutions is approximately 4.2 to 5.3. The osmolality of
both injections is 291 mOsmol. 


-------------


The empirical formula is C14H21N3O2S, representing a molecular weight of 295.4.
Sumatriptan is a white to off-white powder that is readily soluble in water and in saline. Each
IMITREX Nasal Spray contains 5 or 20 mg of sumatriptan in a 100-μL unit dose aqueous
buffered solution containing monobasic potassium phosphate NF, anhydrous dibasic sodium
phosphate USP, sulfuric acid NF, sodium hydroxide NF, and purified water USP. The pH of the
solution is approximately 5.5. The osmolality of the solution is 372 or 742 mOsmol for the 5-
and 20-mg IMITREX Nasal Spray, respectively.

Title: Re: Whacky question
Post by Racer1_NC on Sep 22nd, 2009 at 2:52am
After reading the above, I don't think I'd try it.....but that's just me.....I like living.

Title: Re: Whacky question
Post by Martin on Sep 22nd, 2009 at 9:30am
It does say the powder solution is readily dissolved in water or salt.... and the injection is just the crystal form of the triptan dissolved in salt water.

But really, I took 1 year of chemistry so please ASK A DOCTOR before doing this.  I'd look up to see if injecting the buffered solution would have any negative effects, or if those other additives in the spray would be harmful if injected if you are really keen on accomplishing this.  I understand the need, in the midsts of a hit I've thought about snorting some ground up pills before to make the damn thigns work faster.

I hear 02 works wonders. maybe we should both look into that


Title: Re: Whacky question
Post by seaworthy on Sep 22nd, 2009 at 2:14pm
02 doesn't work well for me and I'm not "keen" on doing this.

I'm desperate.

Title: Re: Whacky question
Post by Ginger S. on Sep 22nd, 2009 at 5:20pm
Did some hunting around for you Seaworthy and here is what I found...


Quote:
Full Question:

Can you inject the nasal spray with a syringe and needle or even through an IV?

The spray is so harsh to my throat. I would rather give myself a shot of this stuff than sniff it.

Thanks or any input, William.
 

Answer:

Dear William;

You didn't specify what medication. Since you tagged your question "Migraine Abortives," it must be Zomig Nasal Spray, Imitrex Nasal Spray, or Migranal Nasal Spray. Whichever it is, the answer is no. Nasal sprays are specifically formulated for nasal delivery and should not be injected.

If you want to try injectable abortives, ask your doctor about Imitrex Nasal spray if you're using Imitrex or Zomig Nasal Spray. If you're using Migranal Nasal Spray, ask about DHE 45 injections. That's the same medication as Migranal, in nasal spray form. These would be injected under the skin. You should never attempt IV injections yourself.

Good luck,
John Claude Krusz and Teri Robert
START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!!  You need to Login or RegisterEND PRINTPAGE


I wouldn't try it given this and the ingredients list beejeeber supplied.

Title: Re: Whacky question
Post by Joni on Sep 22nd, 2009 at 6:46pm
Please do not put the nose spray in an needle for injection into the body.  It contains ingredients that are not in the injectable form.  It is not intended for that use.

Joni   [smiley=sayno.gif]

Title: Re: Whacky question
Post by Brew on Sep 22nd, 2009 at 6:49pm
Can't you just use the inhaler as intended? Or were you trying to extend the small amount you have?

Title: Re: Whacky question
Post by seaworthy on Sep 22nd, 2009 at 7:10pm
Extend a dwindling supply and hasten relief.

Given the info provided in this thread it doesn't appear to be a good idea.

Title: Re: Whacky question
Post by Ginger S. on Sep 22nd, 2009 at 8:51pm
That would be a good conclusion Seaworthy.

Talk to your Neuro he may have samples of different dosages of Imitrex or another option for you.


Title: Re: Whacky question
Post by Joni on Sep 22nd, 2009 at 8:54pm
I just got generic imitrex injections and they are 4mg injections.

Title: Re: Whacky question
Post by MPMIII on Sep 22nd, 2009 at 9:06pm
Seaworthy,
I understand your frustration.  I spend all too much money on imitrex.  My insurance covers 10 shots a month. As a chronic, the least I use in a month is 25. Oxygen works about 50% of the time but it is not always a viable option at work and has never worked on my wake me up from sleep hits. When I read your post I thought " shit, why didn't I think of that?", but based on all the posts, not sure it's a great idea.  Still bouncing the idea around though,  it would ease the financial burden.

Regards,
Malcom 

Title: Re: Whacky question
Post by Ginger S. on Sep 22nd, 2009 at 9:25pm

Joni wrote on Sep 22nd, 2009 at 8:54pm:
I just got generic imitrex injections and they are 4mg injections.

They do have the 6mg injections in the generic as well, that is what I take.

MPMIII You must have better ins. than I do.  Lucky duck!  Chronic here too and ins only allows me 4 shots per mo. even though my Neuro writes the script for more, the bastages!!!   >:(

Title: Re: Whacky question
Post by seaworthy on Sep 22nd, 2009 at 9:53pm

Quote:
Talk to your Neuro he may have samples of different dosages of Imitrex or another option for you.


I already use the highest dosage and other options are not an option.

Title: Re: Whacky question
Post by Lottie on Sep 23rd, 2009 at 5:47pm
Good that you're 'thinking outside the box' to help your CH. That's what desperation forces you to do I think.  :'(

But I'm glad you didn't just try it before looking into it! For most remedy/treatment adjustments I think it's always wise to check with your doc, especially when you're 'experimenting' with medication!

As I read somewhere on this site a while ago: CH doesn't kill you, but wrong/inproper use of medication can!

I think that's a wise statement, and it's good to keep that in mind.

PFDAN,

Lottie

Title: Re: Whacky question
Post by Ginger S. on Sep 23rd, 2009 at 9:10pm
Seaworthy:

Have you tried adding Kudzu herbal supplements to your diet ?  START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!!  You need to Login or RegisterEND PRINTPAGE  It may help lower the number and intensity of the CH hits.  I've added it to my diet and I have noticed a changed for the better!

Also I was suggesting the other lower dosage or SAMPLES as an alternative, if lower dosage sample use 1 1/2 or two shots to kill the beast.  Something is better than nothing when fighting the beast.

Wishing you PFDAN's !!!

Title: Re: Whacky question
Post by seaworthy on Sep 23rd, 2009 at 9:21pm
Thanks but the link doesn't work. Something I would consider though.

Title: Re: Whacky question
Post by Ginger S. on Sep 23rd, 2009 at 9:28pm
Whoops sorry about that

Here's the Fixed link:
START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!!  You need to Login or RegisterEND PRINTPAGE

or just go to

START PRINTPAGEMultimedia File Viewing and Clickable Links are available for Registered Members only!!  You need to Login or RegisterEND PRINTPAGE
and search for Natures Way Kudzu herb.

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