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        New Message Board Archives >> Medications, Treatments, Therapies 2005 >> Trex question
        
(Message started by: astings on Jun 1^st, 2005, 9:04am)

Title: Trex question
Post by astings on Jun 1^st, 2005, 9:04am

Hi all

As we know some people get side effects take trex, Tightness of chest etc, but has anyone who has these side effects, found that splitting the dose greatly reduces these effects?

Pf times for you all

Astings

Title: Re: Trex question
Post by vig on Jun 1^st, 2005, 9:19am

absolutely.
once I cut the dosage in half or a third, the big heart rush was gone, or at least substantially reduced....

Title: Re: Trex question
Post by Bob_Johnson on Jun 1^st, 2005, 9:22am

Headache. 2004 Feb;44(2):178-82.

Frequent triptan use: observations on safety issues.

Robbins L.

Department of Neurology, Rush Medical College, Chicago, Ill. 60062, USA.

OBJECTIVE: To examine the safety of frequent triptan use over extended periods. For a small group of patients with refractory migraine plus chronic daily headache, triptans are effective. METHODS: This retrospective study primarily evaluated the cardiac safety of daily triptan use in 118 patients and, in addition, hematologic tests were assessed. Each patient had utilized a triptan for a minimum of 4 days per week for at least 6 months. Patients with rebound headache had been withdrawn from the triptans. Most patients (97 of 118) averaged 1 tablet daily; most would occasionally go for several days without a triptan. Forty patients had taken a triptan for 6 months to 2 years, 37 patients from 2 to 4 years, and 41 for 4 or more years. RESULTS: Routine hematologic tests were performed periodically on all patients, and no abnormalities were attributable to triptans. Almost all patients had an electrocardiogram, and no abnormal electrocardiograms were felt to be related to triptans. Cardiac echocardiography was performed in 57 patients. The 10 abnormal echocardiograms were not due to triptans. All 20 cardiac stress tests revealed normal findings. Adverse events were minimal; 9 patients described fatigue due to triptans, and 5 had mild chest tightness. CONCLUSION: This long-term study of 118 patients indicates that frequent triptan use may be relatively safe.

PMID: 14756859 [PubMed - indexed for MEDLINE]
------------
The chest tightness is a not uncommon reaction but the reports I've seen say this does not appear to be a sign of heart problems. (This assumes, of course, that you do not have a history of heart disease, etc.)

Title: Re: Trex question
Post by thomas on Jun 1^st, 2005, 9:26am

Look over to the left, see the column of links? The 7th one down is titled "imitrex tip" . You should check it out. ;;D

Title: Re: Trex question
Post by Gator on Jun 1^st, 2005, 2:19pm

I do the dose splitting thing not so much because of any bad feeling the med gives me, but because the stuff is too damned expensive to use more than I need. I tried 1/3 of a shot and it didn't work as well as I would like so I tried half a shot. Works great and I don't get much more than a warm tingly feeling as I feel the trex take effect. Someone best described it as feeling like someone pulling a warm blanket up over your head.

Title: Re: Trex question
Post by astings on Jun 2^nd, 2005, 9:38am

Thanks Guys :)