Clusterheadaches.com Message Board


    
      
        Clusterheadaches.com Message Board
        (http://www.clusterheadaches.com/cgi-bin/yabb/YaBB.cgi)
      

        New Message Board Archives >> Medications, Treatments, Therapies 2004 >> Fresh Research - MS and Headache
        
(Message started by: floridian on Oct 20^th, 2004, 11:16am)

Title: Fresh Research - MS and Headache
Post by floridian on Oct 20^th, 2004, 11:16am

Can't tell much about clusters and multiple sclerosis because this was a small study (137 MS patients), and having one case of clusters is more than one expects, but that could be chance (and you can't get 0.2 clusterheads per thousand with a group of 137 people).

What is interesting is that migraine is more common in people with MS, and that interferon treatments seem to trigger headaches. Other CH research has noted that various interleukins (immune hormones) are out of whack in cluster headache and cervicogenic headache.

Quote:

Cephalalgia. 2004 Nov;24(11):980-4.

Prevalence of primary headaches in people with multiple sclerosis.

D'Amico D, La Mantia L, Rigamonti A, Usai S, Mascoli N, Milanese C, Bussone G.

C. Besta National Neurological Institute, Milan, Italy.

D'Amico D, La Mantia L, Rigamonti A, Usai S, Mascoli N, Milanese C & Bussone G. Prevalence of primary headaches in people with multiple sclerosis. Cephalalgia 2004. London. ISSN 0333-1024The aim was to investigate the lifetime prevalence of headache and primary headache (diagnoses according to International Headache Society criteria) in multiple sclerosis (MS). The relationships between headache and clinical features of MS and MS therapy were also investigated. We studied 137 patients with clinically definite MS; 88 reported headache, 21 of whom developed headache after the initiation of interferon. The prevalence of all headaches in the remaining 116 patients was 57.7%. Migraine was found in 25.0%, tension-type headache in 31.9%, and cluster headache in one patient. A significant correlation (P = 0.007, Fisher's exact test) between migraine and relapsing-remitting MS was found. Primary headaches are common in MS patients. Further studies are needed to clarify the mechanisms underlying this association, particularly the association between migraine and relapsing-remitting MS, and the role of interferon in the development of new headache.