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        Cluster Headache Help and Support >> Medications, Treatments, Therapies >> Cannabinoid studies
        
(Message started by: kcopelin on Feb 7^th, 2007, 6:47pm)

Title: Cannabinoid studies
Post by kcopelin on Feb 7^th, 2007, 6:47pm

Below is the last sentence in the research on the OUCH website on cluster medication research. Anectdotally, people have stated that cannabis is a trigger. This shows that it may not be. That it may in fact help some.
Any port in a storm. I'm not advocating this-or dissing it-just think that when folks show up here and say that smoking pot helps them, they may be right and who the heck am I to argue with aa person who has found something that helps. Crap, I never condemmed the "vinegar and bleu cheese" folks or the "doing 100 push ups" folks, not gonna attack those who think cannabis helps. HOWEVER, it is illegal for the most part and therapuetic doses are probably pretty low (as oppossed to getting really high).

"The data suggest that CB receptors may have therapeutic potential in migraine, cluster headache or other primary headaches, although the potential hazards of psychoactive side-effects that accompany cannabinoid treatments may be complex to overcome."

PMID: 17018694

PFDAN y'all and peace out,
kathy

Title: Re: Cannabinoid studies
Post by JeffB on Feb 7^th, 2007, 7:08pm

When in cycle I stay away from the beer and booze but do not put aside the buds. I find that it's easier for me to get back to sleep after a 2am hit. My clusters are like a time clock and it doesn't matter if I smoked or not I still got hit.
Hope your doing well, Kathy, we need to do lunch soon!

Title: Re: Cannabinoid studies
Post by retrovertigo on Feb 7^th, 2007, 8:43pm

I have heard that pot use releases serotonin and is a vasoconstrictor. One would think the vasoconstriction would positively benefit a CH sufferer. The serotonin release could potentially disrupt circadian rhythms, which would be bad.

That said. it's never seemed to have any effect for me one way or the other. Any booze, even a sip of beer, would result in an instant 10+. But a puff here or there hasn't stopped them or brought them on.

Title: Re: Cannabinoid studies
Post by kcopelin on Feb 7^th, 2007, 10:18pm

Well, Jeff, like "doing lunch" sounds so, I don't know, like totally Californian yuppie....but it seems to me that you mentioned coming up to the north state one of these days....we're not that far away. If you want to go skiing at Mt.Shasta, stop in in Redding-you'll be one hour away from the slopes. Open invitation Jeff.
God bless ya big time with some PFDAN
kathy

Title: Re: Cannabinoid studies
Post by tanner on Feb 7^th, 2007, 10:27pm

Kathy, I have noticed that since I (came out of the closet) about busting that I seem to be getting less responses to my posts then I used to. Probobly just paranoia since I thought that you might have been one of the people I care deeply about and yet I imagined that you were one of those I had "put off" somehow.

No I am not sitting here smoking pot so it must just be old age paranoia ::).

Hugz and best vibes from your buddy.....Tim

Title: Re: Cannabinoid studies
Post by JeffB on Feb 8^th, 2007, 11:33am

on 02/07/07 at 22:18:23, kcopelin wrote:

Well, Honey Bun, If it would friggin snow this year I would be up there just to play around and stop in on you and Ms. Linda.
I've been wanting to go to Dunsmuir since December just for the snow and springs. Make it snow!!!!!!!

Title: Re: Cannabinoid studies
Post by Gator on Feb 12^th, 2007, 8:03pm

You need to also realize that the most of the studies were done with Anandamide (a substance similar to Delta 9 THC) and not by actually smoking pot.

Anandamide has at least two different effects -

1. Acts as a vasodilator = bad for clusters

2. Inhibits trigeminal neurons = good for clusters

We are all different in how we respond to the various medications and substances. Maybe the people for whom pot is a trigger get more of effect #1 and others get more of effect #2.

It could also be that the compound they are using is not as similar as it should be or there may be something else in marijuana that triggers some people but not others.

Either way, it is obvious that marijuana is not a trigger for everyone and therefore if it helps someone cope, even if it is to get a little bit more sleep, more power to them.

Title: Re: Cannabinoid studies
Post by BB on Feb 12^th, 2007, 8:23pm

My only concern is the long term effect of smoking marijuana. There has been evidence that long term and heavy use of pot linked to the development of schizophrenia, paranoia and other forms of mental illnesses in some users.

One can have a relatively normal life with CH, even chronic CH , but not with long term drug use.

Just my 2c.

Annette

Title: Re: Cannabinoid studies
Post by Gator on Feb 12^th, 2007, 9:22pm

Your concern may be warranted, but I don't think anyone here is talking about "heavy" use. Fact is, anything that can be used, can be abused. Alcohol abuse causes severe medical problems and can kill you just as dead as any of the prescription or "illegal" drugs.

Title: Re: Cannabinoid studies
Post by BlueMeanie on Feb 12^th, 2007, 9:50pm

on 02/12/07 at 20:23:01, BB wrote:

Growing up in the 60's and witnessing 100's of ppl who smoke and have smoked, I've never heard of any of them developing schizophrenia, paranoia or any other forms of mental illness. You sure that article wasn't written in the 50's ?
I agree it's a trigger for CH's though.

Title: Re: Cannabinoid studies
Post by nani on Feb 12^th, 2007, 10:18pm

on 02/12/07 at 21:50:20, BlueMeanie wrote:

You sure that article wasn't written in the 50's ?

Or from the movie, Reefer Madness? LOL Recently I've seen studies that indicate that THC may be an effective treatment for depression, and it can slow down, or even prevent the effects of Alzheimer's and certain dementias. Of course... given that...how do you keep from turning into Tommy Chong? ;;D

Title: Re: Cannabinoid studies
Post by froggy on Feb 12^th, 2007, 11:03pm

Hey there,

Been doin' buds for about 30 years, none of my personalities have told me that I have a problem, all systems go!

Tony did try it and it did nothing for him. Interesting study.

Title: Re: Cannabinoid studies
Post by BB on Feb 13^th, 2007, 12:55am

As I have never used any type of drugs, my knowledge and understanding of these substances are purely academic, ie things that I have learnt from one source or another , but not from personal experience.

Also being in my profession, I tend to see only the bad side of drug use ie when people become medically ill with it.

Therefore I freely admit that my view point may be rather biased.

I would like to learn from people who have direct and personal experience with marijuana as to whether it is physically/mentally/emotionally possible for a person to use the drugs recreationally or for medical reason for long term without developing addiction and/or abuse ?

Painfree wishes to all.

Annette

Title: Re: Cannabinoid studies
Post by BikerBob on Feb 13^th, 2007, 2:23am

I wouldn't advocate use of marijuana unless it's for medical purposes.

on 02/13/07 at 00:55:51, BB wrote:

There has been evidence that long term and heavy use of pot linked to the development of schizophrenia, paranoia and other forms of mental illnesses

being in my profession, I tend to see only the bad side of drug use ie when people become medically ill with it.

Therefore I freely admit that my view point may be rather biased.

Annette

In your "profession"; how many people have you seen with schizophrenia, paranoia and other forms of mental illness caused by long term use of cannibinoids? "? How did you treat them? What were your sources when you "learnt from one source or another"?

BB

Title: Re: Cannabinoid studies
Post by Gator on Feb 13^th, 2007, 2:47am

Annette, I toked up pretty regularly in high school. It wasn't one of those things that I breathlessly anticipated doing. It was more of just something my friends and I did when we got together. Hell, I even grew my own in the middle of a large switch cane patch on our property. I carried a 3.89 GPA into my senior year of high school and graduated fourth of 124 students. After high school, I smoked a few times. I enjoyed the feeling I got when I smoked it, but I never did get "hooked" on it. I haven't had any since probably 1982.

I have to admit, I've never seen the movie "Refer Madness," but I have to laugh at the title. Marijuana never did anything for my friends or me, except mellow us out, give us the giggles and the munchies.

Title: Re: Cannabinoid studies
Post by BikerBob on Feb 13^th, 2007, 3:19am

on 02/13/07 at 02:47:44, Gator wrote:

I have to admit, I've never seen the movie "Refer Madness," but I have to laugh at the title.

Here ya go, Gator. It's pretty funny......

http://video.google.com/videoplay?docid=-6696582420128930236

BB [smiley=laugh.gif]

Title: Re: Cannabinoid studies
Post by Kevin_M on Feb 13^th, 2007, 7:29am

on 02/07/07 at 18:47:21, kcopelin wrote:

Below is the last sentence in the research on the OUCH website on cluster medication research

"The data suggest that CB receptors may have therapeutic potential in migraine, cluster headache or other primary headaches, although the potential hazards of psychoactive side-effects that accompany cannabinoid treatments may be complex to overcome."

I see the last sentence of what the data suggest has two parts to it. Whether it is an added warning after the comma or part of what the data suggest is blurry. I would believe it to be perhaps the former.

Title: Re: Cannabinoid studies
Post by BB on Feb 13^th, 2007, 10:22am

on 02/13/07 at 02:23:54, BikerBob wrote:

I wouldn't advocate use of marijuana unless it's for medical purposes.

In your "profession"; how many people have you seen with schizophrenia, paranoia and other forms of mental illness caused by long term use of cannibinoids? "? How did you treat them? What were your sources when you "learnt from one source or another"?

BB

Within the last year alone I saw 3 patients with sudden onset psychotic , brought in by families and were sent by me to the hospital where they were assessed by the psych team and diagnosed with schizophrenia.

They were later discharged back into my care with reports from the Drugs and Alcohol Team, who stated that their long term use of marijuana contributed to the onset of psychosis and possibly the development of schizophrenia. All three were long term heavy users and there is no family history of any form of mental illness.

I cant disclose confidential information but will say that they are now stable on medication. Unfortunately two have gone back to smoking marijuana again.

I do not treat these patients on my own but in conjunction with the teams at the local hospital. Its multidisciplinary involving the Mental Health Team, the Drug and Alcohol Team and the Rehab Team. Occasionally the Medical Tribunal and the Police are also involved.

I learn from many sources, from formal post grad programs to regular programs held at the hospital or by the College of GP, also through medical publications and books and conferences and seminars. I also like to learn directly from people/patients who are users themselves.

Annette

Title: Re: Cannabinoid studies
Post by BB on Feb 13^th, 2007, 10:23am

Thanks Gator for being so frank about your personal experiences :) I really appreciate it ! :-*

Annette

Title: Re: Cannabinoid studies
Post by LeLimey on Feb 13^th, 2007, 10:42am

BikerBob if ever the urge to make a nice post overwhelms you do you think you could give a health warning at the top of it for those of us who may have a coronary?!

Title: Re: Cannabinoid studies
Post by froggy on Feb 13^th, 2007, 11:02am

BB, I definitely see your position.

By no means am I a stoner. I've smoked on and off for quite a while, but like Gator, I don't anticipate having to have it.

I quit smoking during most of High school because I played 3 sports year round, graduated from college, ran my own business for the last 12 years and now am retired at age 40.

Like everything else, thank God everybody is different.

Title: Re: Cannabinoid studies
Post by JeffB on Feb 13^th, 2007, 3:26pm

I guess I should be in a loony bin ;;D

Jeff"I think I'm being followed"B

Title: Re: Cannabinoid studies
Post by LeLimey on Feb 13^th, 2007, 3:34pm

on 02/13/07 at 15:26:52, JeffB wrote:

I'm posting from the loony bin ;;D

Jeff"I hope I'm being followed"B

S'Better ;;D

Title: Re: Cannabinoid studies
Post by JeffB on Feb 13^th, 2007, 3:39pm

:P

Thats it, I'm grabbing my bong and goddies and heading over there.

Title: Re: Cannabinoid studies
Post by echo on Feb 13^th, 2007, 4:45pm

on 02/13/07 at 15:39:45, JeffB wrote:

:P

Thats it, I'm grabbing my bong and goddies and heading over there.

Where are we meeting? I've got a full tank of gas and ready for a road trip?

Title: Re: Cannabinoid studies
Post by JeffB on Feb 13^th, 2007, 5:07pm

You got it echo!

In have known stoners most of my life and none of them have had any mental problems that I know of. Just this weekend I was matching joint for joint a professional that does quite well in business and in life. I think it's more of a stigma thing. Weed is more accepted here in California than in other parts of the country and world. I'm sure there are studies after studies that claim bad side effects or other things it may do to a person but look at cigarettes, alcohol, fatty foods....etc.
All I know is it helps me relax when in cycle and until it no longer does that I'm quite content.

Title: Re: Cannabinoid studies
Post by BB on Feb 13^th, 2007, 8:28pm

on 02/13/07 at 17:07:43, JeffB wrote:

but look at cigarettes, alcohol, fatty foods....etc.

Yup ! I advice against them too :P

In short, what anyone does privately I have no problem with, its when someone arrives at my door unwell that I start to get concerned. 8)

I am definitely not telling people here what to do, I just voice my own opinion on the subject.

Peace.

Annette

Title: Re: Cannabinoid studies
Post by eddie on Feb 14^th, 2007, 12:04pm

amsterdam has class everyday!!!

Title: Re: Cannabinoid studies
Post by UN solved on Feb 21^st, 2007, 2:16am

on 02/12/07 at 20:23:01, BB wrote:

. There has been evidence that long term and heavy use of pot linked to the development of schizophrenia, paranoia and other forms of mental illnesses in some users.

BS. Pure BS I tell ya. Those problems weren't caused by the pot. If they were .. it was the exception and not the general rule.

For me, pot may act as a trigger in a low percentage of times. I could never smoke during an attack.

It is a great anti-depressant. It often helps me get threw the day with little or no worries and anxiety. (Dreading the next attack is no fun either)

But then again, I'm not advocating it since it is an illegal drug. People will just have to weigh the good and the bad here and come up with your own opinions.

Goodluck

UNsolved [smiley=smokin.gif]

PS. Save a bong hit for me fellas !!

Title: Re: Cannabinoid studies
Post by BB on Feb 21^st, 2007, 7:13am

on 02/21/07 at 02:16:30, UN solved wrote:

BS. Pure BS I tell ya. Those problems weren't caused by the pot. If they were .. it was the exception and not the general rule.

UNsolved [smiley=smokin.gif]

PS. Save a bong hit for me fellas !!

I didnt say its the general rule, I just said that there has been evidence showing a link there.

In a way its like cigarette smoking, not everybody who smokes will develop lung cancer or vascular diseases, but some do.

If you can use it for relaxation and it doesn affect you in a negative way then its great! I dont have a problem with that.

Just want to raise the awareness, not being judgemental or anything.

:)

Annette

Title: Re: Cannabinoid studies
Post by rbmb on Feb 21^st, 2007, 8:42pm

I find a little pot at the end of the day is a great way to relax. The key is moderation, just like with drinking. I don't smoke it if I have something important to do or if I have to drive somewhere. While mowing the lawn or working on some little project.....yes. While figuring out my taxes.....no. I've never noticed any bad effects from it other than my short term memory goes to hell (and my short term memory isn't too good any time. It's also a nice relaxant when you are in cycle and can't touch alcohol.
Rich

Title: Re: Cannabinoid studies
Post by BMoneeTheMoneeMan on Feb 24^th, 2007, 12:41pm

Annette,
No offense, i am not trying to break your balls or anything:
But you have officially been propagandized.

Pharmey companies used marijuana for years until the USA outlawed it. The list of medical uses for marijuana goes on and on. Granted, smoking it unfiltered is bad for the lungs, but eating it, drinking it and making pills of the resin has been around for centuries.

Eli Lilly and Parke Davis made multiple preparations of tinctures and pills and at least 28 different preparations of cannabis were marketed when cannabis as medicine was outlawed in 1937.

I am sure you can find studies that show that organized religion causes psychosis. I am sure you can find studies that show how fresh cow's milk causes multiple personality disorders.

There are many strains of the marijuana plant, some strains are better for certain conditions than others. For example, a mostly indica or purely indica plant can help with restless legs syndrome. It also is one of the best anti-vomit medications out there for people on chemo.

The Mayo Clinic says there is a 3% risk for addiction, which is less than most other pharmaceuticals.

If a doc gave you or Daniel a choice: Either take 30 mg of hydrocodone and 10 mg of oxycodone per day, or injest 4 grams of marijuana per day, which one would you pick if both were projected to have the same effect?

PF wishes
BMonee

Title: Re: Cannabinoid studies
Post by BB on Feb 24^th, 2007, 3:54pm

No offense taken at all $Man :-*

Its all a matter of education and I did say clearly that my view on this maybe biased as I dont have any personal experience of the substance nor have witnessed anyone close using it. All that I have seen personally are people who seem to have become quite seriously ill with it.

I am well aware of the medicinal uses of the marijuana. I simply dont know what is the difference between how it is used creationally and therapeutically, whether how you use it would make a difference, but I am sure how much and how often you use it would definitely make a difference.

For eg, narcotics when used as a pill or muscular injection medically have different effects than when injected directly into a vein by a drug user. Furthermore when used therapeutically as a medicine, there is at least some form of control as to the frequency and quantity being used, while when used recreationally there may not be such a control.

There maybe perhaps a magic formula that combines certain physical bodies with certain mental capacities with certain dosages used and certain length of time used that will spell trouble for people? Guess no one knows that magic formula yet.

In comparison, alcohol can be consumed quite safely and merrily and has pretty good effect to relax and unwind people. However, if it taken enough in quantity for a long enough time, it can send people into a coma and death, or can render a person an alcoholic.

Guess in short, using substances such as alcohol, marijuana or even hardcore drugs like cocaine and amphetamine, the key issue is control. Control over how, how much and how long. Loss of that control is when trouble strikes.

My 2 cents

Annette

Title: Re: Cannabinoid studies
Post by BMoneeTheMoneeMan on Feb 24^th, 2007, 4:46pm

I agree, Annette, moderation is key to justs about everything....including moderation.

What is your opinion on long term narcotic use for ligitimate pain? For example, lets pretend that vicodin or percocet were good treatments for CH. Would you want Daniel taking those drugs several times per day with each hit?

Do they use these drugs on a long term basis in Oz?

PF wishes
B$

Title: Re: Cannabinoid studies
Post by BB on Feb 24^th, 2007, 5:25pm

They use sustained release morphine for long term chronic pain here in Australia for other conditions such as arthritis, back pain, etc.

I have talked to the Pain clinics here about long term pain control for chronic CH and they use either sustained release morphine, slow release tramadol, fentanyl or methadone. However, that is the last resort. They try everything else first from hypnotism to relaxation techniques to nerve blocks, etc.

There are currently studies on the use of marijuana as pain killers but not CH.

In the past, for a period of time, when Daniel was very unwell and suicidal, he was taking pain killers ( morphine ) 3-4 times a day after the bad hits as he couldnt cope. He was seen by the Pain clinic and the Psychiatrist and they agree on that regime for a little while. It was either that or he would have killed himself, literally. Once he physically hurt me so that he could grab the car keys off my hands as he wanted to drive away and into a truck! The police and ambulance were called and he was taken to hospital. Not much difference from what happened yesterday to Dave really. ( The only difference is that he wouldnt have posted that on any Board. I only learnt about his plan because I was watching him like a hawk ). They were going to keep him in hospital but he absolutely refused. He hates doctors and hospitals just like most other CHers. He refused to stay and he told me if I wouldnt take him home he would have discharged himself against medical advice and he did. The end result was I had to take 6 months off work to stay home to look after him. The narcotics did not stop the pain, he just floated above it. It was a VERY hard journey going down from that regime and it was hell for several weeks before he became "clean" from it.

If there are studies to confirm that marijuana can be safely and effectively used for CH pain then believe me, I would not hesitate to recommend it. The same goes with alternative treatments such as shrooms and seeds. Unfortunately we are not at that stage yet.

Annette

Title: Re: Cannabinoid studies
Post by froggy on Feb 24^th, 2007, 8:54pm

Wow Annette,

How close to home is all of that. I am soooo glad you guys are coming out of it all.

Title: Re: Cannabinoid studies
Post by JJA on Mar 1^st, 2007, 12:55pm

on 02/12/07 at 20:23:01, BB wrote:

Ok, take your copy of Reefer Madness out of the VCR. ;;D

First, I am very involved in drug policy reform and know a lot of long-term drug (cannabis) users that live a much more "normal" life than a lot of CH'ers. They have good jobs and normal children.

Second, you are somewhat correct about cannabis causing schizophrenia. Well kinda...
There is a definite link between cannabis consumption and schizophrenia and most researchers in the field think that cannabis can cause schizophrenia, but only in at-risk adolescent users. There is no good way to know definitely if you are "at-risk" (having schizophrenic 1st degree relatives is a red flag), but it is easy to tell if you are an adolescent (just pull a tooth and count the rings ;)).

However, it has not been proven that cannabis causes schizophrenia vs pre-schizophrenics self-medicating with cannabis. There is one huge flaw in the theory that cannabis causes schizophrenia. About 40 years ago the rate of cannabis consumption increased nearly 2000% (hippies!). The schizophrenia rate should have also risen. That has not been the case (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=12821204&query_hl=5&itool=pubmed_docsum). The rate of schizophrenia has been around 1% of the population for as long as it’s been studied.

Basically, if you are over age 18, there is no risk of cannabis causing schizophrenia. If you are younger, there is a very small risk, and the younger you are the greater the risk.

Title: Re: Cannabinoid studies
Post by JJA on Mar 1^st, 2007, 12:58pm

For those interested in a more technical anaysis:

There certainly is an abnormality in the endocannabinoid system of schizophrenics.

Quote:

Recent longitudinal studies from Sweden, the Netherlands, New Zealand, and Israel report that cannabis use during childhood and adolescence doubles the risk of later appearance of psychosis or schizophrenia. These data have been interpreted as indicating that cannabis has a causal effect along the pathway to psychosis. In this paper, we will offer an alternative explanation of these data. Recent investigations of patients with schizophrenia found increased density of cannabinoid receptors in the dorso-lateral prefrontal cortex and the anterior cingulate cortex. Others reported higher levels of endogenous cannabinoids in the blood and cerebrospinal fluid of patients; these findings were independent of possible cannabis use. Several genetic studies have reported an association between genes encoding the cannabinoid receptor and schizophrenia. Thus, an alternative explanation of the association between cannabis use and schizophrenia might be that pathology of the cannabinoid system in schizophrenia patients is associated with both increased rates of cannabis use and increased risk for schizophrenia, without cannabis being a causal factor for schizophrenia.
Interpreting the association between cannabis use and increased risk for schizophrenia. Weiser, M and Noy, S(2005) (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16060598&query_hl=9&itool=pubmed_DocSum)

Probably the most well known study that claims to show that cannabis causes schizophrenia is the "New Zealand Study", Tests of Causal Linkages Between Cannabis use and Psychotic Symptoms (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed)” (Fergusson et al, 2005). This study uses advanced statistical modeling to control for confounding variables (where an unknown or an uncontrolled variable effects both cannabis use and psychotic symptoms) and reverse causality (For the purposes of this study, reverse causality is limited to self-medicating after symptoms are present).

Fergusson uses 3 models to attempt to control for confounding variables. I have taken advanced statistics, but this paper uses what I assume are doctorate level stats to make their case. My guess is that most people, including researchers that read this paper gloss over the complicated statistical modeling without understanding it. This is exactly what I did the first time I read it. Recently, I took some time to understand exactly what they are doing and what assumptions they make. These are my conclusions and I welcome anyone to critique my critique. The first 2 models control for specific confounds such as age, sex, child abuse, socioeconomic status, deviant peers, etc. We can ignore these models for this purpose. The third model, “the conditional fixed effects model,” attempts to correct for unknown confounding variables such as genetics. However, fixed effects model makes an important assumption. It assumes that confounding variables are constant over time as is the case with genetics. But is it true for endocannabinoid abnormalities? Considering that this is taking place in developing adolescents we can assume that it is not fixed. To make long story short, this would not control for reverse causality in a developing (changing) adolescent.

Henquet et al. (2005) found that "psychosis liability" predicted future cannabis use and vise versa. Psychosis liability in this study is defined as having already experienced a psychotic symptom (not those that have schizophrenic 1st degree relatives). Those who have had psychotic symptoms are more likely to use cannabis, compared to “normal” people. Among those "psychosis liable" people, those that do consume cannabis are more likely to develop full-blown schizophrenia. These results were repeated by Ferdinand et al. (2005) and they make the following conclusion: “The results imply either a common vulnerability with varying order of onset or a bi-directional causal relationship between cannabis use and psychosis.

Basically all this means that it is unknown whether or not cannabis causes schizophrenia.

Title: Re: Cannabinoid studies
Post by chrisw on Mar 1^st, 2007, 1:28pm

hi im new here,
I recently went to jamaica and I was in the middle of a cluster cycle, i tried some pot and got aan instant 10 ha. Just be careful.
chris

Title: Re: Cannabinoid studies
Post by JeffB on Mar 1^st, 2007, 1:37pm

on 03/01/07 at 13:28:44, chrisw wrote:

hi im new here,
I recently went to jamaica and I was in the middle of a cluster cycle, i tried some pot and got aan instant 10 ha. Just be careful.
chris

Maybe it's a trigger for you. But if you were in a cycle you were going to get a ha anyway, right?

Title: Re: Cannabinoid studies
Post by nani on Mar 1^st, 2007, 7:42pm

on 02/24/07 at 17:25:44, BB wrote:

He hates doctors and hospitals just like most other CHers.

[smiley=huh.gif] That must not bode well for your marriage, Annette. LOL
BTW, I don't hate doctors or hospitals.

on 03/01/07 at 12:55:17, JJA wrote:

About 40 years ago the rate of cannabis consumption increased nearly 2000% (hippies!).

You're welcome. ;;D
Hi Jesse!!! :-*

Title: Re: Cannabinoid studies
Post by BB on Mar 1^st, 2007, 7:52pm

on 03/01/07 at 19:42:56, nani wrote:

[smiley=huh.gif] That must not bode well for your marriage, Annette. LOL
BTW, I don't hate doctors or hospitals.

Hi Nani,

One would think so wouldnt they ? Ask him and he says he sees me as his wife and not his doctor, plus to him its great that I can sometimes help him from having to go see another doc and that I may be able to prevent him having to go to hospital.

His reasoning, not mine. 8)

I am glad you dont hate doctors and hospitals :)

Annette

Title: Re: Cannabinoid studies
Post by nani on Mar 1^st, 2007, 7:58pm

It must be a spousal thing... My sister is married to an MD. She really doesn't think of him as a dr either... but mostly because she's thinks he's an idiot, LOL. ;)

Title: Re: Cannabinoid studies
Post by JJA on Mar 1^st, 2007, 8:12pm

on 03/01/07 at 19:42:56, nani wrote:

Hi Jesse!!! :-*

[smiley=wave.gif]

Title: Re: Cannabinoid studies
Post by BB on Mar 1^st, 2007, 8:21pm

on 03/01/07 at 19:58:52, nani wrote:

It must be a spousal thing... My sister is married to an MD. She really doesn't think of him as a dr either... but mostly because she's thinks he's an idiot, LOL. ;)

LOL ! Poor guy ...

Daniel thinks I am wonderful, especially at meal times ;;D

Annette

Title: Re: Cannabinoid studies
Post by thebbz on Mar 1^st, 2007, 9:15pm

Boy this thread is really going to pot! lol [smiley=laugh.gif] [smiley=laugh.gif]
I hate doctors and hospitals equally. ;;D
Doctors are like cops: Theres never one around when you need one. ::)
No offense to any docs here. :P
jb

Title: Re: Cannabinoid studies
Post by froggy on Mar 2^nd, 2007, 1:38am

We usually are not the biggest fans of many of the doctors we've seen over the years.

But I have to say our neurologist of 2 years here in South Carolina rocks. He listens, he tries and is always up for trying the "new" next thing we come up with.