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        Cluster Headache Help and Support >> Medications, Treatments, Therapies >> Testesterone injections
        
(Message started by: unsolved1 on Sep 1^st, 2006, 11:43pm)

Title: Testesterone injections
Post by unsolved1 on Sep 1^st, 2006, 11:43pm

I'm also now going to try taking 100mg injections of testosterone every 2 weeks for awhile and see what happens. I have taken 2 injections so far. I haven't noticed any bad side effects ... but I'm not sure it's helped any yet either. Will keep trying.

BTW...my levels were in the 'low-normal' range to begin with.

Anyone else ?

UNsolved

Title: Re: Testesterone injections
Post by paulc on Sep 2^nd, 2006, 2:32am

Interesting treatment for CH! Let us know if "it" gets any larger or if your sex drive increases. My internist said that testosterone has nothing to do with CH-I, and I'm sure others-would be interested to know what happens.

Title: Re: Testesterone injections
Post by Bob_Johnson on Sep 2^nd, 2006, 8:07am

Headache. 2006 Jun;46(6):925-33.

Testosterone replacement therapy for treatment refractory cluster headache.

Stillman MJ.

Objectives.-To describe the clinical characteristics and laboratory findings of cluster headache patients whose headaches responded to testosterone replacement therapy. Background.-Current evidence points to hypothalamic dysfunction, with increased metabolic hyperactivity in the region of the suprachiasmatic nucleus, as being important in the genesis of cluster headaches. This is clinically borne out in the circadian and diurnal behavior of these headaches. For years it has been recognized that male cluster headache patients appear overmasculinized. Recent neuroendocrine and sleep studies now point to an association between gonadotropin and corticotropin levels and hypothalamically entrained pineal secretion of melatonin. Results.-Seven male and 2 female patients, seen between July 2004 and February 2005, and between the ages of 32 and 56, are reported with histories of treatment resistant cluster headaches accompanied by borderline low or low serum testosterone levels. The patients failed to respond to individually tailored medical regimens, including melatonin doses of 12 mg a day or higher, high flow oxygen, maximally tolerated verapamil, antiepileptic agents, and parenteral serotonin agonists. Seven of the 9 patients met 2004 International Classification for the Diagnosis of Headache criteria for chronic cluster headaches; the other 2 patients had episodic cluster headaches of several months duration. After neurological and physical examination all patients had laboratory investigations including fasting lipid panel, PSA (where indicated), LH, FSH, and testosterone levels (both free and total). All 9 patients demonstrated either abnormally low or low, normal testosterone levels. After supplementation with either pure testosterone in 5 of 7 male patients or combination testosterone/estrogen therapy in both female patients, the patients achieved cluster headache freedom for the first 24 hours. Four male chronic cluster patients, all with abnormally low testosterone levels, achieved remission. Conclusions.-Abnormal testosterone levels in patients with episodic or chronic cluster headaches refractory to maximal medical management may predict a therapeutic response to testosterone replacement therapy. In the described cases, diurnal variation of attacks, a seasonal cluster pattern, and previous, transient responsiveness to melatonin therapy pointed to the hypothalamus as the site of neurological dysfunction. Prospective studies pairing hormone levels and polysomnographic data are needed.

PMID: 16732838

Title: Re: Testesterone injections
Post by chopmyheadoff on Sep 4^th, 2006, 4:04am

i have used test for bodybuilding. in much higher doses than you are using.

can i ask which test you are using ??

test propionate, enanthate ??

if you have any questions, worries feel free to ask

Title: Re: Testesterone injections
Post by chopmyheadoff on Sep 4^th, 2006, 4:11am

BTW - "it" wont get larger - no matter how much test you inject. This is a myth along with many others.

your testicles may shrink - but with such a low dose this is unlikely - and completely reversible on quitting the therapy.

other common side effects would be an increase in sex drive, acne (maybe on the upper back, shoulders and face), increased masculinity (broadening of the shoulders and muscle mass increase), hair will grow faster, you may find you sweat more.

again, all these symptoms depend on the ester of testosterone that you have been given. Please specify