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Cluster Headache Help and Support >> Medications, Treatments, Therapies >> Users of verapamil and migranal
(Message started by: FramCire on Aug 22nd, 2006, 10:13am)

Title: Users of verapamil and migranal
Post by FramCire on Aug 22nd, 2006, 10:13am
I was perscribed these 2 drugs together and then when a doctor was doing some research for me found this:

     
[Migranal/verapamils]

avoid combo: combo may incr. risk of ergot toxicity, severe vasospasm and ischemia (hepatic metab. inhibited)



Yet another wonderful drug interaction.  On another unrelated note, I still haven't found an anti-depression medication that either doesn't trigger CH or interact with triptans.


Title: Re: Users of verapamil and migranal
Post by brewcrew on Aug 22nd, 2006, 10:18am
I was in the hospital two weeks ago for the DHE-45 treatment, and the doctors there continued to give me verapamil (240 mg, 2x/day). Seems they either don't know about this interaction, or it's bunk. I seemed to have no ergot toxicity, severe vasospasm, or ischemia.

Title: Re: Users of verapamil and migranal
Post by E-Double on Aug 22nd, 2006, 10:41am

on 08/22/06 at 10:13:09, FramCire wrote:
I was perscribed these 2 drugs together and then when a doctor was doing some research for me found this:

      
[Migranal/verapamils]

avoid combo: combo may incr. risk of ergot toxicity, severe vasospasm and ischemia (hepatic metab. inhibited)



Yet another wonderful drug interaction.  On another unrelated note, I still haven't found an anti-depression medication that either doesn't trigger CH or interact with triptans.

http://www.drugs.com/xq/cfm/pageID_1150/int_1/list_1/values_drugid%3Dd00048%26drugid%3Dd00211%26/OpText_Migranal/dr_%2Cverapamil%2CMigranal/qx/index.htm
No interactions found.
I have not heard of this either and considering they have opposite effects I wouldn't think that this was a correct statement, however I am not a doctor or a pharmacist or a matchmaker or a cobbler or a mandingo warrior.

Title: Re: Users of verapamil and migranal
Post by FramCire on Aug 22nd, 2006, 1:35pm
I spoke with my doctor this morning who says he has percribed this combo for years without any problems.  However, the site i got this from is one I KNOW other doctors use for interactions.  (epocrates?)

Anyway, it could be wrong.


Title: Re: Users of verapamil and migranal
Post by Chronic on Aug 22nd, 2006, 1:36pm
I am currently on Migranol and Verapamil and have had no problem.  Today i am switching to DHE 45 Injections instead of Migranol.  These Chronic Clusters have been a real bitch lately...nothing is keeping them under control.  Anyway, I have read about no problems with combining the two

Title: Re: Users of verapamil and migranal
Post by Karla on Aug 27th, 2006, 1:01am
You mentioned you thought triptans interact with antidepressants.  Can you tell me more about this?  I have been on anti depressants and trex and other triptans for several years.  While at the same time taking such antidepressants as wellbutrin, celexa,effexor, and cymbalta.  Currently on effexor.
I also take antiphycotics which I know interact with melatonin so I cant take that.  I have geodon,abilify, seroquel.  I need these meds.  So any info you can give me about drug interactions would be benifitial to know what I am getting myself into.  Thanks.



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