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        Cluster Headache Help and Support >> Medications, Treatments, Therapies >> Has anyone heard of this?
        
(Message started by: ClusterChuck on Aug 16^th, 2006, 12:38am)

Title: Has anyone heard of this?
Post by ClusterChuck on Aug 16^th, 2006, 12:38am

I was just told about a new treatment for (dare I mention the “M” word?) migraines. From what I have been told, it has been approved in Russia and in the UK. It is a one time shot that you get (in your butt) and it stops migraines, supposedly, forever.

Now, it is true that clusters are NOT migraines, but we all know that some migraine meds work for us, too. Has anyone heard of this new treatment? The drug is called, LARDACGACTYL. I hope that is the right spelling, as I am getting the information third or fourth hand. I cannot get any answers when I check in Google, nor in rxlist.com.

Does this ring a bell to any of our “over the waters” family members?

I am posting this to both the medical and general boards to get the fullest dispersal.

Chuck

Title: Re: Has anyone heard of this?
Post by chopmyheadoff on Aug 16^th, 2006, 2:34am

not heared of this yet . .

wouldnt it be nice if we could have a one off shot to kill the beast forever . . . :)

Title: Re: Has anyone heard of this?
Post by georgej on Aug 16^th, 2006, 3:08am

on 08/16/06 at 02:34:48, chopmyheadoff wrote:

wouldnt it be nice if we could have a one off shot to kill the beast forever . . . :)

I know of one, but I can't recommend it. The main side effect being a dirt nap. Not that it hasn't crossed my mind a time or two...

But...no.

Let us know if you find anything out, Chuck. BTW, I referred a couple of ER residents to your video the other night--the more non-CH'rs who see and understand (at least a little) the better. Maybe somewhere down the line it will save some poor SOB a little pain.

Hope you don't mind.

George

Title: Re: Has anyone heard of this?
Post by BB on Aug 16^th, 2006, 8:44am

Could it be LARGACTIL ?

Which is Chlorpromazine hydrochloride , an antipsychotic drug similar to Zyprexa ( Olanzapine ) which is also used to abort cluster attack. Its also in the same class as Lithium.

Maybe a Largactil injection can abort a migraine/cluster attack but I am not so sure about the "forever" bit.

Annette

Title: Re: Has anyone heard of this?
Post by chopmyheadoff on Aug 16^th, 2006, 8:48am

iv heared of largactil before.
some of my more unsavoury friends who have been in jail say that they give this to the more "hyperactive" prisoners.

they are effectionately known as "shufflers" because the lads who have them do nothing except shuffle around all day.

take from this what you will :-/

Title: Re: Has anyone heard of this?
Post by unsolved1 on Aug 16^th, 2006, 10:38am

Is this the same drug as Thorazine ?? [smiley=huh.gif]

I won't touch Thorazine again !!

UNsolved

EDITED TO ADD: after reading the other post ... Gator put up some info adding that this is Thorazine.

My comment: THIS IS A NASTY DRUG !! DON'T DO IT !!

Title: Re: Has anyone heard of this?
Post by serendipity on Aug 16^th, 2006, 11:14am

This is a little off-topic, but did anyone else read LARDACGACTYL as "LARDASGACTYL"? Perhaps since Chuck mentioned it was a shot to the butt, I was expecting to see the words "LARD ASS" in there somewhere.

Title: Re: Has anyone heard of this?
Post by rickyshot on Aug 16^th, 2006, 11:33am

I have had Largactil (sp) a couple of times in ER via IV years ago and it did NOT agree with me at all or help. I know I am a tough case but just giving y'all my antedotal experiences. I think I have been on every med and alternative treatment known to man sigh.......

Title: Re: Has anyone heard of this?
Post by Gator on Aug 16^th, 2006, 12:25pm

Here is my post from the General Board that unsolved was talking about:

Could you be talking about Largactil? If so, I see nothing about it being a one time cure all for migraines. Here is what I did find...

http://www.migraines.org/treatment/prothora.htm

Quote:

Chlorpromazine (aka Thorazine, aka Largactil) is often used to treat the nausea and vomiting and, to some extent, the pain associated with a Migraine attack. It also allows the Migraineur to rest more easily and allows other medications to work better.

General information about Chlorpromazine:
Phenothiazines (FEE-noe-THYE-a-zeens) are used to treat serious mental and emotional disorders, including schizophrenia and other psychotic disorders. Some are used also to control agitation in certain patients, severe nausea and vomiting, severe hiccups, and moderate to severe pain in some hospitalized patients. Chlorpromazine is used also in the treatment of certain types of porphyria, and with other medicines in the treatment of tetanus. Phenothiazines may also be used for other conditions as determined by your doctor.

Phenothiazines may cause unwanted, unattractive, and uncontrolled face or body movements that may not go away when you stop taking the medicine. They may also cause other serious unwanted effects. You and your doctor should talk about the good this medicine will do as well as the risks of using it. Also, your doctor should look for early signs of these effects at regular visits. Your doctor may be able to stop or decrease some unwanted effects, if they do occur, by changing your dose or by making other changes in your treatment.

While I ve never tried it, have heard nothing good about Thorazine.

And yes, I did expect to see "Lard Ass" in the name of the drug when I first read the post on the General Board. LOL

Title: Re: Has anyone heard of this?
Post by rhino on Aug 20^th, 2006, 9:29pm

Chuck,, I got all excited reading you post,, jumped up telling my wife were going to Russia,, grab your fur coat.
Then I read everybody else post,, what a bummer.
Keep looking and stay in touch,, I feel like shit tonight,
I have been shadowing all day long. I would give anything if I could get a shot of lard ass and feel good. :-/

Title: Re: Has anyone heard of this?
Post by paul2006 on Aug 21^st, 2006, 8:13pm

As far as I can recall, Largactyl is now banned in the UK.

Title: Re: Has anyone heard of this?
Post by BB on Aug 22^nd, 2006, 1:38am

Talked to a friend of mine who told me that his dad was diagnosed with major depression with psychotic episodes, was prescribed Largactil and committed suicide a month later, last year.

He said his mental state deteriorated markedly after starting Largactil, but no one knows if its the medication that tipped him over.

Annette

Title: Re: Has anyone heard of this?
Post by Karla on Aug 22^nd, 2006, 8:13am

Thorazine makes me feel violently ill and just wild feeling in general. I would not recomend it to anyone. It does nothing for migraines or ch. At least that is my experience.