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New Message Board Archives >> Oct-Dec 2003 >> Attention telefoon call from Glaxo
(Message started by: J.ten_Dam on Nov 6th, 2003, 11:10am)

Title: Attention telefoon call from Glaxo
Post by J.ten_Dam on Nov 6th, 2003, 11:10am
I have plased this massage on the medical board as well. Attention telefoon call from Glaxo
« on: Today at 9:25am »  Quote  Modify  Remove  

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as I mentiond on the 5 under Glaxo and 1/2 imitrax auro injector
« on: Nov 5th, 2003, 7:04am » I have emaild them yesterday  and today I was phoned by a gentilman from the research department.
http://www.gsk.nl/watwedoen/klinischonderzoek/ does research on ilness and medication.  
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He informd me that a survay had been done a while ago and the result was that not meny people had benifit in lower dosage!!!!!!!!!!!.
Now pease  let us show them that it is not so. Annyone using the Imitrax tip Please sen these people an e-mail stating wether you are cronik or episodik. Why you resort to using lower dosagees and how long you have been doing this and also mention whether it is as effective as the normal dosage. The more E-mails they get the sooner they will restart the tryals which were planed anywhay because they have been getting feed back from neurologists that mention that their patients are using lover dosages.




Title: Re: Attention telefoon call from Glaxo
Post by Mark C on Nov 6th, 2003, 11:28am
I am all for lower doses for several reasons. One being I should be able to treat more HA in a 24 hour period without exceeding the recommeded dosage. Another is to make what little Imitrex I get last a little longer. However.....I do not believe Glaxo would lower the price of a lesser dose for one thing, and I think that is one of the reasons for a smaller dose..less money would be nice.

Having been researching Imitrex Injection more in-depth just recently the 6mg dose came after studys shown that was the ideal dose to treat migrains. Even at doses of 12mg and even 18 mg no siginificant decrease in pain occured....with migrains.

From what I have read on this board many achieve relief with as little as 2mg dose. In this kind of treatment less is more to me.

A small dose applicator from Glaxo would not surprise me....a decrease in price would.

FYI...I had a Neurologist appointment today and since I am lucky enough to have both the Auto-Injector and the single use vials I asked about halfing the dose using the vials. The reply was since these are single use vials are indeed single use, Imitrex injection has no preservative and she is worried about not only the safety of the Imitrex but also the sterilty of re-using a single use vial. I still intend on trying a half dose, carefully....with a new syringe each time.

PFDAN's
Mark
 

Title: Re: Attention telefoon call from Glaxo
Post by J.ten_Dam on Nov 6th, 2003, 11:52am
Hi mark why not mention this in an e-mail to glaxco. Who knows what they will say. By the way in holland the survay was done with clusterheads as wel as migrainers

Title: Re: Attention telefoon call from Glaxo
Post by Mark C on Nov 6th, 2003, 12:00pm
J-Ten,
I think I will, what do we have to lose but some pain?

PFDAN's
Mark

Title: Re: Attention telefoon call from Glaxo
Post by Jayne on Nov 6th, 2003, 12:56pm
This worries me ...for people who DON"T have health insurance. I am sure if Glaxo made lesser dosages..the price would not lower that much. At least with the tip we can get more for our $ if you know what I mean.
Then you would have problems with doctors understanding prescribing the lower dosage...how many we actually need. I am happy to use the tip and save some money on each headache.
I think this lower dose pack from glaxo has potential of coming back to bite us in the arse eventually. Don't forget they are a BUSINESS and want to make money, they don't really give a rats arse about the individual and how much pain they go through and how much they have to pay through the nose to lessen that pain.
*stepping off my soap box*:-)

Title: Re: Attention telefoon call from Glaxo
Post by vig on Nov 6th, 2003, 2:16pm
What did we get for receiving a $2,500 'donation' from Glaxo?

How long does it take for Glaxo to make that $2,500 back from us on CH.com at $70 a pop?

5 seconds?  10?

Maybe we need to consider that Glaxo is not an ally in  our cause.

How many people here have I read about that are in SERIOUS financial trouble from buying Imitrex?

I think we should send the $2,500 back to them.

Am I the only one?

Paul

Title: Re: Attention telefoon call from Glaxo
Post by thomas on Nov 6th, 2003, 2:21pm
No, you are not alone vig.

Title: Re: Attention telefoon call from Glaxo
Post by Mark C on Nov 6th, 2003, 2:36pm
Well lets not be TOO hasty.....my Neruro gave me about $2000 (!) in samples this morning and because of my insurance (which I pay for) I am able to get $1280 of Imitrex injection for an $80.00 co-pay. Don't get me wrong...I hate drug companies almost as much as Attorneys....but they do have the Trex!

I am changing my tune as we speak as to what really works and what side effects are worth the trouble.

Oh yeah....Glaxo is gonna get rich anyway so you may as well buy some stock!  ;;D

Onward through the fog!
Mark

Title: Re: Attention telefoon call from Glaxo
Post by vig on Nov 6th, 2003, 2:47pm
A good crack dealer gives out plenty o' crack before the cha-ching begins...

Title: Re: Attention telefoon call from Glaxo
Post by thomas on Nov 6th, 2003, 3:14pm
[smiley=smug.gif]I need the cha-ching to get my bling-bling.

Title: Re: Attention telefoon call from Glaxo
Post by Mark C on Nov 6th, 2003, 3:29pm
I tried crack...it cost more and my head still hurt!

8)


Seriously though, I don't believe for a minute Glaxo exists to better the condition of Humanity.....however....I still get a bunch of free meds every visit to the Doc. If I didn't I would run out, even with letters from my Doc and such.

Point taken vig  :)

Later yall,
Mark

Title: Re: Attention telefoon call from Glaxo
Post by floridian on Nov 6th, 2003, 3:40pm
I see no problem in accepting money from Big Pharmacy as long it doesn't  require any compromise (and I don't see any happening).  Maybe alternative funding could be sought from someone like gazillionare phillanthropist George Soros. He was a big backer of the medical mary jane initiatives.  Medical mushrooms make sense, but this is such a 'rare' disease, and US drug policy is dominated by emotion and hysteria, not reason.

Title: Re: Attention telefoon call from Glaxo
Post by Charlie on Nov 6th, 2003, 4:59pm
Since these drug company criminals executives harp about needing so much loot for research, it's time we volunteer to be a part of it. We'd be tickled pink to join in an effort to explore all the effects and whatnot of Imitrex and other drugs. Just supply the stuff and we'd go nuts participating in dosages and ways to administer the stuff.  You want ideas about it? We got 'em by the freight car load. :o

If only we lived in Oz.  >:(

Charlie

Title: Re: Attention telefoon call from Glaxo
Post by vig on Nov 6th, 2003, 5:07pm
One of the biggest problems here (as I see it) is the price of medicine, and Imitrex is the big one.  

They refuse to lower the price.
They refuse to make Imitrex available in the doses we need.

They have done nothing in reality to help our cause except pretend to be a sponsor and by accepting the money, we tacitly agreed to their claim.  They gave us the $2,500 to shut us up.

Title: Re: Attention telefoon call from Glaxo
Post by Prense on Nov 6th, 2003, 6:29pm

on 11/06/03 at 17:07:03, vig wrote:
One of the biggest problems here (as I see it) is the price of medicine, and Imitrex is the big one.  


The biggest problem is the monopoly...

Title: Both Right!
Post by floridian on Nov 6th, 2003, 7:21pm
Only a monopoly allows the price to be set so high.  The patent/copyright IP system keeps getting adjusted to extend the monopoly.  

People believe that modern patent medicines are more effective than the old snake oil cure, but I wonder - is snake oil anything like fish oil or flax oil??  

Title: Re: Attention telefoon call from Glaxo
Post by Mark C on Nov 6th, 2003, 8:00pm
The table below sets out patent expiry dates for the active ingredients in significant GlaxoSmithKline products.    
     
Therapeutic area Product Active ingredient(s) Patent expiry dates for active ingredient(s) in major countries  

CNS disorders Seroxat/Paxil paroxetine During or after 2006
Wellbutrin bupropion  Basic compound patents have expired. Formulation patents will expire during or after 2013
Imigran/Imitrex sumatriptan During or after 2003 (USA 2006)
Naramig/Amerge naratriptan During or after 2010
Lamictal lamotrigine During or after 2005
Requip ropinirole During or after 2007  
Zyban  bupropion  Basic compound patents have expired. Formulation patents will expire during or after 2013

There were quite a few more, Look here. (http://www.gsk.com/financial/reports/ar/report/descrip_of_bus/intell_property/intell_prop.html)

For some reason I am not sure this is going to help us much. It looks like Glaxo is losing quite a few lucrative patents in the next few years.....hard on their bottom line. I reckon they must keep discovering (inventing) new drugs to maintain the monoply. It's all about the Benjamin.

PFDAN's
Mark

Title: Re: Attention telefoon call from Glaxo
Post by floridian on Nov 6th, 2003, 8:56pm
Lately the patent medicine companies have gotten a couple years of extension by challenging anyone who wants to make a generic in court.  The patent holders ultimately lose, but keep things tied up for an extra billion or two.  Generic companies are being bought up and suddenly decide to stick with aspirin.  Other generic companies have negotiated contracts so that they get paid more not to manufacture a newly expired patent generic than they could make by manufacturing that med - after all, they don't need production facilities to not produce something, so its pure profit.  Other than that, everybody wins.

Title: Re: Attention telefoon call from Glaxo
Post by Patrick_A on Nov 7th, 2003, 12:43am
Its kind of like a 2 liter bottle of Coca-Cola. The actual soda cost about 2 cents to make, and the plastic bottle that it comes in is another 5 cents. Its the marketing that cost the large percentage.
Did you know that Drug companies have a slush fund for drugs gone bad? Lets say that Imitrex 20 years down the road is found to have created heart problems and some Tort lawyers decide to sue Glaxco. Glaxco of course will fight like hell to keep from having to pay, but if they do have to pay, it just comes from the slush fund.
Why do ya reckon Imitrex cost $70.00 a pop!
Just something to think about!

Patrick



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