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        Cluster Headache Help and Support >> Cluster Headache Specific >> rebound
        
(Message started by: mickey on Nov 10^th, 2006, 9:19pm)

Title: rebound
Post by mickey on Nov 10^th, 2006, 9:19pm

I've been taking three to four shots daily. I'm getting rebounds. If I quit taking Imetrex., how long before rebounds stop?

Title: Re: rebound
Post by E-Double on Nov 10^th, 2006, 9:35pm

try the tip http://www.clusterheadaches.com/imitrex.html

if you are finding an increase in attacks then try the above or an alternative.

Oxygen is a kick a$$ abortive for MANY

Zyprexa is another alternative which has not had the same nasty side effects as trex for quite a few of us

Title: Re: rebound
Post by artemis on Nov 10^th, 2006, 9:40pm

Zyprexa? I've been reading way too much today...I thought I saw where that causes blindness or psychological problems...got enough of those already. Does Zyprexa really work? I mean, it sounds good...
at least it doesn't involve needles, right?
artemis

Title: Re: rebound
Post by E-Double on Nov 10^th, 2006, 9:59pm

Quote:

Headache: The Journal of Head and Face Pain
Volume 41 Page 813 - September 2001
doi:10.1046/j.1526-4610.2001.01148.x
Volume 41 Issue 8

Olanzapine as an Abortive Agent for Cluster Headache
Todd D. Rozen, MD
Objective.—To evaluate olanzapine as a cluster headache abortive agent in an open-label trial.

Background.—Cluster headache is the most painful headache syndrome known. There are very few recognized abortive therapies for cluster headache and fewer for patients who have contraindications to vasoconstrictive drugs.

Methods.—Olanzapine was given as an abortive agent to five patients with cluster headache in an open-label trial. The initial olanzapine dose was 5 mg, and the dose was increased to 10 mg if there was no pain relief. The dosage was decreased to 2.5 mg if the 5-mg dose was effective but caused adverse effects. To be included in the study, each patient had to treat at least two attacks with either an effective dose or the highest tolerated dose.

Results.—Five patients completed the investigation (four men, one woman; four with chronic cluster, one with episodic cluster). Olanzapine reduced cluster pain by at least 80% in four of five patients, and two patients became headache-free after taking the drug. Olanzapine typically alleviated pain within 20 minutes after oral dosing and treatment response was consistent across multiple treated attacks. The only adverse event was sleepiness.

Conclusions.—Olanzapine appears to be a good abortive agent for cluster headache. It alleviates pain quickly and has a consistent response across multiple treated attacks. It appears to work in both episodic and chronic cluster headache.

Title: Re: rebound
Post by BB on Nov 11^th, 2006, 12:10am

on 11/10/06 at 21:40:51, artemis wrote:

No Artemis, Zyprexa doesnt cause blindness as a direct side effect. There was some confusion on that thread you read. Its Lyrica that has double vision and blurry vision as side effect.

Annette

Title: Re: rebound
Post by artemis on Nov 11^th, 2006, 9:13am

All right thanks doc and thanks e-double! that sounds like a keeper then-but is in tablet form, nasal spray or shots? I really hope its not shots- and doc thanks for being here when it sounds like you got a lot of other stuff to do. I'm really amazed at how much everyone helps everyone else here.
pfdan (pain free days and nights)
artemis

Title: Re: rebound
Post by Bob_Johnson on Nov 11^th, 2006, 9:27am

Zyprexa is in pill form--one of the advantages when away from home, etc.

Title: Re: rebound
Post by mickey on Nov 11^th, 2006, 12:36pm

What should I ask the doc for ?
Olanzapine as an Abortive Agent for Cluster Headache
or Zyprexa or are they the same ?

Title: Re: rebound
Post by E-Double on Nov 11^th, 2006, 2:40pm

on 11/11/06 at 12:36:36, mickey wrote:

What should I ask the doc for ?
Olanzapine as an Abortive Agent for Cluster Headache
or Zyprexa or are they the same ?

zyprexa is a brand name like imitrex vs sumatriptan ;)

Title: Re: rebound
Post by dannyboy on Nov 15^th, 2006, 10:10am

Not to interupt this great thread...

Funny thing about rebound

According the IHS classification rebound can only be positively diagnosed if the headache condition improves after you stop the offending drug. There is a time period for the measurement, a month or two.

What this is essentially means is that you can only diagnose rebound retrospectively. Or in other words you can never be diagnosed as having rebound, you can only be diagnosed as having had it.

Retarded indeed.

Small wonder the last editor of Cephalagia said that the IHS classification was the greatest hinderence to the progress of headache science.

Rock on Clusterville

Danny

Title: Re: rebound
Post by chopmyheadoff on Nov 16^th, 2006, 2:16am

on 11/15/06 at 10:10:34, dannyboy wrote:

[smiley=nono.gif]
[smiley=slowlaugh.gif]

Title: Re: rebound
Post by Carl_D on Nov 19^th, 2006, 8:37am

Imitrex puts me in rebound hell!!!

Frova tabs (a different form of triptan) take longer to kick in, but chewing one up and letting it sit under the tongue for about 10 minutes will get it into the bloodstream faster, though tastes nasty. I've noticed with the Frova I have less frequent attacks and can go a day or two in between sometimes even.

I was on Zyprexa a few years ago but it didn't do much of anything for me.

Peace,
Carl