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New Message Board Archives >> 2005 Cluster Headache Specific Posts >> Research: Obesity as a Risk Factor for Apnea/CH
(Message started by: floridian on Jun 30th, 2005, 11:17am) |
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Title: Research: Obesity as a Risk Factor for Apnea/CH
Post by floridian on Jun 30th, 2005, 11:17am
Nothing too surprising - the apnea research has long shown that extra weight is a risk factor for apnea. In this study, clusterheads had an 8x risk of apnea, while those with a high BMI (overweight) had a risk that was 24x higher than the general population.
As a drop in blood oxygen can trigger clusters, sleep apnea is an apparent trigger. Apnea isn't the cause of clusters, but it seems that more weight = more pain for some people.
Quote:Cephalalgia. 2005 Jul;25(7):488-92.
Investigation into sleep disturbance of patients suffering from cluster headache.
Nobre M, Leal A, Filho P. Department of Neurology, Universidade Federal Fluminense, Niteroi, Brazil.
Nobre ME, Leal AJ & Filho PMF. Investigation into sleep disturbance of patients suffering from cluster headache. Cephalalgia 2005. London. ISSN 0333-1024 The new discoveries relating to cluster headache (CH) encouraged the study of the relationship of the hypothalamus to respiratory physiology and its comorbidity with sleep apnoea. The question is whether the apnoeas are more frequent during REM sleep and the desaturations could be involved as triggers of the cluster attacks. Furthermore, could the connection with the hypothalamus, already proved, be responsible for an alteration in the structure of REM sleep and a chemoreceptor dysfunction. We set out to analyse when polysomnography investigation is necessary in patients with CH. We studied 37 patients suffering from episodic CH, 31 (83.8%) men and six (16.2%) women. For the control group, we selected 35 individuals, 31 (88.6%) men and four (11.4%) women. There was a greater percentage of obstructive sleep apnoea (OSA) in patients with CH (58.3%) compared with the control group (14.3%) and with the general population (2-4%). In cases of pain during sleep, the majority is deflagrated during the REM phase, following a desaturation episode. A stratified analysis of the apnoea/hypnoea index relating to body mass index (BMI) and age showed that patients with CH have 8.4 times more chance of exhibiting OSA than normal individuals (P < 0001). This risk increases to 24.38 in patients with a BMI > 25 kg/m(2) and increases to 13.5 in patients > 40 years old. Surprisingly, the risk decreases sharply in patients with a BMI < 25 kg/m(2) and who are < 40 years old. Due to the fact that polysomnography is a complex, costly and sometimes difficult examination, we suggest, in concordance with the results, that it should be carried out routinely in patients with CH that exhibit a BMI of > 25 kg/m(2) and/or in patients who are > 40 years of age. |
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Age is also a risk factor - can anyone help me lose some years. ;) |