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Title: Histamines & CHs Post by Bucco on Jun 2nd, 2004, 10:07am As a result of reading the responses to my previous ER message I made my first trip to the OUCH website. I couldn't understand the technical discussions I found there to any great degree. However, there was a mention of Histamines there that caught my eye. I have had elevated histamines for many years ( I have to take a pil a day (Zyrtec) to keep from getting rashes and itching.... basically allergy control. Does anyone know of a more detailed discussion of the relationship between Histamines and CHs that they can refer me to??? [smiley=huh.gif] |
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Title: Re: Histamines & CHs Post by UN_SOLVED on Jun 2nd, 2004, 10:44am Cluster headaches are also sometimes called Histamine headaches. "no specific cause has been found for the disorder, but it appears to be related to a release of histamine, serotonin, or similar substances from body tissues." I've heard some neuro's say that a "Histamine drip therapy" might stop a cycle while others say it will make you worse. I've never had it done. Too afraid of the outcome. Here are a few links that may help. http://health.allrefer.com/health/cluster-headaches-info.html http://www.healthcentral.com/mhc/top/000786.cfm http://www.meldrum.demon.co.uk/migraine/clusterfaq3.txt http://www.vbmc.org/ency/article/000786.htm Unsolved |
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Title: Re: Histamines & CHs Post by ave on Jun 3rd, 2004, 6:32am Never had any type of allergy in my life - still got clusters. Take into account that a great many people have allergies, but only a tiny percentage of the population have clusters. So... |
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Title: Re: Histamines & CHs Post by floridian on Jun 3rd, 2004, 10:02am Histamine is one of many inflammitory substances that are elevated during a cluster attack - others include substance P, nitric oxide, CGRP, several bradykinins. Some people report that anti-histamines help them, others get little or no relief from that type of med. Given the low cost and known side effects profile, antihistamines may be worth a try. Quote:
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Drugs like cromolyn and nutrients like quercetin & quercetrin (in apples, onions, other fruits and veggies) are mast cell stabilizers - they make mast cells less eager to dump their histamine packages. This approach has even fewer side effects than histamine blockers, which can cause drowsiness etc. Mast cell stabilizers and histamine blockers work by different mechanisms, but I'm not sure off hand if they can be taken together. |
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Title: Re: Histamines & CHs Post by Ueli on Jun 3rd, 2004, 12:38pm I've had some bad experience with histamine. I love our hard, fully ripened Swiss cheese (not to be confused with the blubbery surrogate offered in American stores). It has some histamines in it (and therefore is on the M. trigger list), but they usually don't harm me, I eat cheese every day for breakfast. However, a few times when I added a bread and cheese snack to my midnight beer to be prepared for a long TV session, I was hit with a monster attack of 3 hours. I later learned that alcohol speeds up the uptake of histamines a hundredfold, and the resulting histamine burst was strong enough to trigger a giant attack. BTW, the gurus of the DMKG (German Headache Society) list antihistamines among the "ineffective or obsolete" treatments. PFNADs Ueli [smiley=smokin.gif] |
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Title: Re: Histamines & CHs Post by floridian on Jun 3rd, 2004, 1:35pm Here's another mast cell stabilizer - pycnogenol. Pycnogenol is derrived from pine bark. Grape seed extract often has similiar effects, although there is more natural variation in grape products. While normal antihistamines (histamine blockers) take effect quickly, cromolyn/quercetrin/pycnogenol take time to work - a week or two at full dose is usually needed for a mast cell stabilizer to become fully active. Quote:
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