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Title: Imitrex patent expires.... Post by Mark C on Aug 13th, 2003, 8:36am ......in three years. I bet that is good news for us! Gotta bring the price down. Pharmaceuticals The table below sets out patent expiry dates for the active ingredients in significant GlaxoSmithKline products. Therapeutic area Product Active ingredient(s) Patent expiry dates for active ingredient(s) in major countries CNS disorders Seroxat/Paxil paroxetine During or after 2006 Wellbutrin bupropion Basic compound patents have expired. Formulation patents will expire during or after 2013 Imigran/Imitrex sumatriptan During or after 2003 USA 2006/08 Naramig/Amerge naratriptan During or after 2010 Lamictal lamotrigine During or after 2005 Requip ropinirole During or after 2007 Zyban bupropion Basic compound patents have expired. Formulation patents will expire during or after 2013 Respiratory Flixotide/Flovent fluticasone propionate During or after 2003 Serevent salmeterol xinafoate During or after 2003 USA 2008 Seretide/Advair fluticasone propionate & salmeterol xinafoate Patents covering the combination will expire during or after 2010 Flixonase/Flonase fluticasone propionate During or after 2003 Anti-bacterials Augmentin co-amoxiclav Basic compound patents have expired, with the exception of the USA (2017), France (2002) and Italy (2007) Zinnat/Ceftin cefuroxime axetil Patents to cefuroxime axetil per se have generally expired, although SPCs exist in Europe until 2002. Patents on the amorphous form of cefuroxime axetil will expire during or after 2003 Fortum/Fortaz ceftazidime Basic compound patents have expired Amoxil amoxycillin Basic compound patents have expired Anti-virals Combivir lamivudine + zidovudine Patents on the combination of the two active ingredients will expire during or after 2012 Epivir lamivudine During or after 2009 Retrovir zidovudine Basic compound patents have expired. Patents on use in HIV infection will expire during or after 2005 Ziagen abacavir During or after 2009 Agenerase amprenavir During or after 2013 Valtrex valaciclovir During or after 2009 Zovirax aciclovir Basic compound patents have expired Zeffix/Epivir-HBV lamivudine During or after 2009 Relenza zanamivir During or after 2013 Metabolic and Avandia rosiglitazone During or after 2013 gastro-intestinal Zantac ranitidine Basic compound patents have expired Oncology and emesis Zofran ondansetron During or after 2005. During or after 2006 for patents to its use in emesis Looks like many good drugs are going to get cheaper and GSK may be in a bind without new drugs to keep the cash cow going like it has. PFDAN's Mark |
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Title: Re: Imitrex patent expires.... Post by vig on Aug 13th, 2003, 8:40am "Looks like many good drugs are going to get cheaper and GSK may be in a bind without new drugs to keep the cash cow going like it has. " which means they will keep the price as high as they can until it expires. |
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Title: Re: Imitrex patent expires.... Post by catlind on Aug 13th, 2003, 9:03am Of course the expiration of the patent on imitrex is discussed in the convention report as well ;) Not the details that you provided, just the fact that the patent will expire. Cat |
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Title: Re: Imitrex patent expires.... Post by MOBster on Aug 13th, 2003, 1:46pm Well I can't see many drug companies coming out of the woodwork to produce a generic version of Imigran/Imitrex ? It's not just the drug that's important but the well researched and well trialed delivery system. Which I may add is under patient to Glaxo for another ten years ! From what I have been told most drug companies would find the cost of inventing, trialing and producing a new or similar delivery system prohibitive. Hence no mad rush by drug companies to do it :o and we thought Glaxo were slipping :-X Best Wishes, Michael (MOB) 8) |
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Title: Re: Imitrex patent expires.... Post by catlind on Aug 13th, 2003, 4:40pm Mob, my understanding is that's why they have changed their stat dose system to the new one. Regardless of the stat dose system, I use vials and a needle. That method of delivery is not only cheap, it's already available the world through. While you may not get a stat dose reproduced under generic names, I can imagine that many other pharm co's would be chomping at the bit to release a generic version that is simply in a vial. JMHO though :) Cat |
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Title: Re: Imitrex patent expires.... Post by MOBster on Aug 14th, 2003, 3:11am Hi Cat, There will always be a way around auto injectors Cat ;) But I don't think there will be any rush to produce Imigran/Imtrex in vials by anyone or any other med for that matter. The medical community are moving away from vials and administering medications that way because of the inherent risks involved. There are 800,000 needlestick injuries and potential exposures to bloodborne pathogens occurring each year in the US. As recommended by your own Occupational Safety and Health Administration's (OSHA) newly revised bloodborne pathogens standard. The new Safety Tip-Lok all-in-one delivery system is already in use for Hepatitis A and B vaccines in hospitals. This of course is already spreading to many other areas because of peoples fears (always a good selling point)about cross infection and obviously the GSK machine both heightening and allaying those fears in one :o The 'wave of the future' will as usual be a lot more expensive than the past - JMHO :'( Best Wishes, Michael (MOB) |
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Title: Re: Imitrex patent expires.... Post by Ted on Aug 14th, 2003, 3:25am You may be right MOB. The thing is that there is no liability lawsuit if a needlestick injury occurs. Not if you get your own prescription and administer it yourself. That's how most of it will be administered. It will still be very profitable for GK to produce it and the generic companies to reproduce it. Those are staggering figures you gave here but they will have minimal impact on it being reproduced. Now, if they can produce it with a chemical that will help me I'll be very happy (Read, since it doesn't help me I have no horse in this race and therefore am not coming from the "I hope" POV) |
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Title: Re: Imitrex patent expires.... Post by MOBster on Aug 14th, 2003, 4:09am Shit Ted I thought you had changed your username to Guest ? ;D CGRP's sound like your only hope then Ted and it aint much at the moment :( Better watch Ted ;) you are a newbie now ;D Best Wishes, Michael |
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