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marlinsfan
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CH Gene found in Italy?!?
« on: Aug 23rd, 2005, 1:22pm »
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So, once in a while I go to the Italian OUCH web site to see how things are going on that side of the planet. Their web site is:
 
http://www.grappolaiuto.it/
 
In one of the forums today I see an article published by La Stampa, a recognized magazine, which states that Dr. Lorenzo Pinessi, director of the Neurology Dept of teh Headache Center of Molinette, discovered that the gene that causes CH is one called Hcrtr2. Here is a link for those who read italian:
 
Link to thread:
http://www.grappolaiuto.it/yabbse/index.php?board=1;action=display;threa did=2181
 
Link to the actual article:
http://www.lavetraia.com/Zaira/articologene.gif
 
It also states that this has been published in the US magazine called Neurology.
 
Has anyone heard of this news?
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Re: CH Gene found in Italy?!?
« Reply #1 on: Aug 23rd, 2005, 1:39pm »
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Here are a bunch of sites.
http://www.google.com/search?hl=en&q=cluster+headache+gene
 
Here is the actual "Neurology" mention:
 
http://www.neurology.org/cgi/content/abstract/63/7/1286
« Last Edit: Aug 23rd, 2005, 1:41pm by E-Double » IP Logged

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Re: CH Gene found in Italy?!?
« Reply #2 on: Aug 23rd, 2005, 2:03pm »
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on Aug 23rd, 2005, 1:22pm, marlinsfan wrote:
... which states that Dr. Lorenzo Pinessi, director of the Neurology Dept of teh Headache Center of Molinette, discovered that the gene that causes CH is one called Hcrtr2.  
 

 
Hcrtr2 is not THE gene that causes CH, it is one gene that increases the risk. It is possible to have CH without that gene, and not everyone with that gene gets CH. But it is good to know which genes are linked to increased risk, because that helps us figure out the puzzle.  
 
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Re: CH Gene found in Italy?!?
« Reply #3 on: Aug 23rd, 2005, 4:49pm »
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Australian scientiests this week found the gene involved in migraine. They expect to know much more about it within a year or so and suggest it may well even lead to a 'cure' within five years.
 
 
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Re: CH Gene found in Italy?!?
« Reply #4 on: Aug 24th, 2005, 7:19am »
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on Aug 23rd, 2005, 4:49pm, AussieBrian wrote:
Australian scientiests this week found the gene involved in migraine. They expect to know much more about it within a year or so and suggest it may well even lead to a 'cure' within five years.

 
This is exciting news... Smiley
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Re: CH Gene found in Italy?!?
« Reply #5 on: Aug 24th, 2005, 7:33am »
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This is exciting news!  Wouldn't it be wonderful if medical science could prove this, and somehow find a way to eliminate the gene, or neutralize it.  I'm gonna send prayers and vibes to those docs!!!!
 
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Re: CH Gene found in Italy?!?
« Reply #6 on: Aug 24th, 2005, 1:14pm »
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Fuckin' find the fuckin' cure already, cause I'm fuckin tired of that fuckin shit ruining my fuckin nights and fuckin shit! Angry
« Last Edit: Aug 24th, 2005, 1:14pm by rextangle » IP Logged
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Re: CH Gene found in Italy?!?
« Reply #7 on: Aug 24th, 2005, 3:17pm »
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on Aug 24th, 2005, 1:14pm, rextangle wrote:
Fuckin' find the fuckin' cure already, cause I'm fuckin tired of that fuckin shit ruining my fuckin nights and fuckin shit! Angry

 
 Cry    hug
 
Perhaps it's time for another trip to the post office?   Wink  Kiss  hugs to you, honey, nani
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Re: CH Gene found in Italy?!?
« Reply #8 on: Aug 24th, 2005, 3:25pm »
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on Aug 24th, 2005, 1:14pm, rextangle wrote:
Fuckin' find the fuckin' cure already, cause I'm fuckin tired of that fuckin shit ruining my fuckin nights and fuckin shit! Angry

 
We'll forward your request to the medical community and see how they respond. I thought the limit was 4 F-bombs per sentence, but you've clearly raised the bar to 6, even punctuating the last one with the exclamation point. Wording it the way you have I'm certain the medical community will understand in a more clear fashion why they should get on with finding a "cure" for us.
 
Scott
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Re: CH Gene found in Italy?!?
« Reply #9 on: Aug 24th, 2005, 3:53pm »
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on Aug 24th, 2005, 1:14pm, rextangle wrote:
Fuckin' find the fuckin' cure already, cause I'm fuckin tired of that fuckin shit ruining my fuckin nights and fuckin shit! Angry

 
I will translate this to Italian and post it over there Grin
 
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Re: CH Gene found in Italy?!?
« Reply #10 on: Aug 24th, 2005, 4:11pm »
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Who is this "Gene" and where does he live? I want to kick him in the yambag about a hundred times!  Angry mad
 
Or maybe I'll buy him a shiny new bicycle!
http://www.clusterheadaches.com/cgi-bin/yabb/YaBB.cgi?board=general;acti on=display;num=1124917423
« Last Edit: Aug 24th, 2005, 4:22pm by Jeepgun » IP Logged

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Re: CH Gene found in Italy?!?
« Reply #11 on: Aug 25th, 2005, 7:51am »
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Quote:
CH Gene found in Italy?!?

 
So thats where the little bastard has been hiding.
 
Lucky you Italians dont have oil reserves or we would bomb your country.  
 
For a noble cause of course.
« Last Edit: Aug 25th, 2005, 7:51am by don » IP Logged
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Re: CH Gene found in Italy?!?
« Reply #12 on: Aug 25th, 2005, 3:52pm »
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on Aug 24th, 2005, 1:14pm, rextangle wrote:
Fuckin' find the fuckin' cure already, cause I'm fuckin tired of that fuckin shit ruining my fuckin nights and fuckin shit! Angry

 
 
I know where you are at,  Rex.   I feel putout with it all too.  Hang in there buddy.  Rest easy,  we're here for you.
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Re: CH Gene found in Italy?!?
« Reply #13 on: Aug 26th, 2005, 4:29am »
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CH Gene
If you spot him, whack him with a canolli.
 
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Re: CH Gene found in Italy?!?
« Reply #14 on: Aug 26th, 2005, 11:39am »
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Scott... LMAO!
 
I apologize for my regular punkrock moments...
When my head is sore I have a very short fuse and go in my "fuckin" rampage... or occasionally blame the F***ing Post Office for all the miseries of the world....
 
But if the medical community is interested in my reaction, let them read the fucking post already!!! Wink
 
I like the Italian name for CH... Cefalea a Grappolo!!!
 
I'm gonna start telling people that I have Cefalea a Grappolo instead of Cluster Headaches...
 
Gimme Cappuccino and Cefalea a Grappolo!!!!  Grin
« Last Edit: Aug 26th, 2005, 11:41am by rextangle » IP Logged
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Re: CH Gene found in Italy?!?
« Reply #15 on: Aug 26th, 2005, 11:52am »
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on Aug 26th, 2005, 11:39am, rextangle wrote:
I like the Italian name for CH... Cefalea a Grappolo!!!
 
I'm gonna start telling people that I have Cefalea a Grappolo instead of Cluster Headaches... Grin

 
I like that too. It needs a short pause after it is spoken, a shifting of the eyes to the left and right and an organ chord played like in the silent films.
 
"What is it?"
"It's the Cefalea a Grappolo (pause - look right and left - organ chord)"
"No (arm to forehead, head backward), not that (faints  at the news)"
 
I like it very much -- what's the proper pronunciation -- anyone know Italebonics that can help?
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Re: CH Gene found in Italy?!?
« Reply #16 on: Aug 26th, 2005, 12:01pm »
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You're too funny man!!!! LOL Grin
 
Or you can do the french version...
 
Hold a glass of red wine and a Gitane cigarette and say (with strong french accent):
 
- Non! it iz ze algie vasculaire de la face bourgeois yankee bastard!
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Re: CH Gene found in Italy?!?
« Reply #17 on: Aug 26th, 2005, 12:11pm »
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LMAO, Rex!
 
Vowels in Italian are the same as in Spanish.
 
a - Like the first "o" in octopus
i - Like "i" in "onion"
u - Like the "u" in "tube"
e - Like the "a" sound in "bay"
o - Like the "o" in "row"
 
(edited for clarification)
« Last Edit: Aug 26th, 2005, 1:40pm by Jeepgun » IP Logged

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Re: CH Gene found in Italy?!?
« Reply #18 on: Aug 26th, 2005, 1:30pm »
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on Aug 26th, 2005, 12:11pm, Frank_W wrote:
LMAO, Rex!
 
Vowels in Italian are the same as in Spanish.
 
a - Like the "o" in octopus
i - Like "i" in "onion"
u - Like the "u" in "tube"
e - Like the "a" sound in "bay"
o - Like the "o" in "row"

Dang! That language is worse than English. Sure glad I was born speaking American.
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Re: CH Gene found in Italy?!?
« Reply #19 on: Aug 26th, 2005, 5:46pm »
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on Aug 26th, 2005, 11:52am, seasonalboomer wrote:

I like it very much -- what's the proper pronunciation -- anyone know Italebonics that can help?

 
chef-A-lea a gra-PPO-lo
 
that looks funny. Cefalea is pronounced like CHEF l(ike the cook), but with a strong C, then accent on the A, then soft lea " chef-A-lea". Then Grappolo is with a accent on the PPO, with exageration on the P, that' why it's 2 ps.
 
I'm confusing everyone. Must be the 30 hours without power after hurricane Katrina that has my brain fried.
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