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Topic: Imigran (trex) nasals dosage (Read 431 times) |
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pubgirl
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Does anyone here know why the Imigran(trex) nasals are such a high dose at 20mg?
Every other way of administering triptans is much lower than this and research suggests only small amounts of a triptan are needed to stop attacks.
I ask because although they work very quickly for me, I am not enjoying some nasty side effects from them when I VERY rarely use them and it feels as if the dosage is too high for my body
Wendy
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LasVegas
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Re: Imigran (trex) nasals dosage
« Reply #1 on: Aug 23rd, 2005, 10:51pm » |
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Pretty sure it is the concentration of the dosage and how fast the medicine gets to the bloodstream.
RE: Imitrex/Imigran...
i.e. Injections...6mg (fastest to bloodstream)
Inhaler....20mg (fast to bloodstream)
Tablets.....50mg or 100mg....(not as fast to bloodstream compared to above)
Hope this helps....Gregg in Las Vegas
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mcf69
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Re: Imigran (trex) nasals dosage
« Reply #2 on: Aug 23rd, 2005, 11:01pm » |
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It has to do with the rate of absorption through the nasal membranes. Alot of the dose is lost due to dripping, mucus flow etc, therefore a higher dose is needed to achieve the desired results. Too bad there wasn't a way of dividing it up like with the injectables though......
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LasVegas
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Re: Imigran (trex) nasals dosage
« Reply #3 on: Aug 26th, 2005, 1:33am » |
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Inhale every drop and swallow it!
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don
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Re: Imigran (trex) nasals dosage
« Reply #4 on: Aug 26th, 2005, 4:21am » |
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Quote:| Inhale every drop and swallow it! |
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If you do that the med isn't getting through the nasal membrane where it supposed to go.
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pubgirl
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Re: Imigran (trex) nasals dosage
« Reply #5 on: Aug 26th, 2005, 4:39am » |
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and I want LESS Imigran, not more via my stomach!
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eyes_afire
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Re: Imigran (trex) nasals dosage
« Reply #6 on: Aug 26th, 2005, 9:26am » |
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If I'm not mistaken, there is a 5mg dosage size (although I've never seen it so I can't confirm its existence).
http://www.rxlist.com/cgi/generic/sumatnas_ids.htm
--- Steve
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LasVegas
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Re: Imigran (trex) nasals dosage
« Reply #7 on: Aug 26th, 2005, 10:35pm » |
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on Aug 26th, 2005, 4:21am, don wrote:
If you do that the med isn't getting through the nasal membrane where it supposed to go. |
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It is already in the nasal membrane Don...when it starts to congest or drip after a minute or two...breath in deeply, do not blow out into kleenex, and swallow the med....works for me 10 out of 10 times!!!
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Kevin_M
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Re: Imigran (trex) nasals dosage
« Reply #8 on: Aug 27th, 2005, 8:39am » |
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It would take longer through stomach digestion. Nasal absorption would be more important at 20mg when waking with it underway playing catch up.
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Karla
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Re: Imigran (trex) nasals dosage
« Reply #9 on: Aug 27th, 2005, 4:22pm » |
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I have taken 10 mg imitrix ns before and it works. My dr. will write me out scripts for injections, 20 and 10 mg ns. That helps and works wonders. I will take 10 mg and if after 10 min ha still there I take another 10mg else if ha gone I don't. Try it you will like it.
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Karla
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icculus
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Re: Imigran (trex) nasals dosage
« Reply #10 on: Aug 31st, 2005, 1:50pm » |
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i have found that with the nasal spray, you want as much as you can to absorb through the nose:
1) it works quicker
2) doesnt taste as bad
3) doesn't effect stomach
4) IT WORKS QUICKER!!!
just pinch of the nostral and pray....
after a year pf, i am now on week #4 of 2-3 per day, and the nasal spray is loosing effectiveness...
everything that i find that works, eventually becomes inadequate. switched to the injections and am looking into O2.
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pubgirl
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Re: Imigran (trex) nasals dosage
« Reply #11 on: Aug 31st, 2005, 5:25pm » |
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Saw GP today and have ditched the Imigran nasals as I am sure they are too strong for me. I am genuinley not trying to make you jealous because our medical system is different and you probably can't afford all these but she is great and has armed me with a barrage so I can choose to use what I think is best depending on the circumstances (she thinks, quite rightly, that I know more about CH than she does and she is a good enough doctor secure in her own abilities not to mind!)
1st Line attack: Have enough 02 to last weeks-large and portable tanks + 2 of Ben's special kit for delivery (it's the best!)
2nd Line attack: Have Frova or Zomig pills to choose from while using 02 to try and block attacks for a while and buy some sleep- Frova still having some useful prophylactic reports from other sufferers.
3rd Line attack:Imigran injections and Zomig nasals for emergencies
The blessed woman has put them all on 5 repeats as well so I can order 5 more times without an appointment.
I LOVE my GP!
Wendy the Brit- armed and DANGEROUS! watch out Beast, I IS READY FOR YOU NOW!
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