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Topic: Re: Rivea Corymbosa (LSA) Tonights Test (Read 2278 times) |
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Candycane
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #1 on: Jun 18th, 2005, 6:52am » |
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Having a hellish week, for first time for awhile now I am wishing I was back on my preventives. I am chromic and 02 doesn't work well for me. Had one of those if I had a gun nites this week, LOL Anyway I am outa seeds and yesterday ordered some more but not those, wish I had, maybe today I will order some more and order a RUSH  please keep us informed how its working.
Running out my trex injections, thinking about Zomig? Don't know alot about it I will read. I know info is here just my eyes have been working for shit this week.
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| « Last Edit: Jun 18th, 2005, 6:55am by Candycane » |
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nani
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #2 on: Jun 18th, 2005, 10:39am » |
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Candy, I may be wrong, but wouldn't using trex (or any triptan )affect the way the seeds work? Is it possible that it's not working well right now because of trex? I'm sure someone who knows will be along ... I'm just wondering. Hang in there, hun. You are stronger than it is. hugs, nani
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Chillrmn1
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #3 on: Jun 18th, 2005, 10:57am » |
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Hi Nani,
Good point, based on what's been brought up previously, I think have to agree with you, I am no expert. I believe 1 is an agonist and 1 is an antagonist. Not sure though, waiting to see a more expert response to this.
EDIT - Or does the trex block the LSA from the receptors until detoxed?
Bob
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| « Last Edit: Jun 18th, 2005, 11:00am by Chillrmn1 » |
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Langa
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #4 on: Jun 18th, 2005, 11:15am » |
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Quote:| EDIT - Or does the trex block the LSA from the receptors until detoxed? |
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Good question. I thought this was the reason we were asked to detox from the get to?
CC, were you detoxed from the trex and how long before you dosed the first time?
Langa
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Candycane
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #5 on: Jun 18th, 2005, 12:04pm » |
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Yes, I was TOTALLY detoxed from everything for about 3 or more weeks now????? And was doing good but I think I screwed up not doing maintenance doses and by then I was rockin with them (sorta speak) Guess I am fucked now for awhile til they back off and I get my new seeds 
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Pinkfloyd
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #6 on: Jun 18th, 2005, 1:16pm » |
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on Jun 18th, 2005, 12:04pm, Candycane wrote:| Yes, I was TOTALLY detoxed from everything for about 3 or more weeks now????? And was doing good but I think I screwed up not doing maintenance doses and by then I was rockin with them (sorta speak) Guess I am fucked now for awhile til they back off and I get my new seeds |
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Just to clarify...
Are you running out of trex because you "were" running out before you stopped using it or because you have resumed using it now that the attacks have again picked up?
Bobw
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Candycane
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #7 on: Jun 18th, 2005, 1:33pm » |
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Okay....Whole story about 3 weeks ago I started on the seeds was detoxed. They worked like a charm for 3 weeks,which is really good for me. Did not dose at all or do anything in that 3 weeks. Then finally started getting hit soooo did some more seeds ( didn't work) by then I was getting BLASTED so YES I am a wimp I have done alot of trex this week. I wish my obligations could just stop when I am that bad and in my car driving children but it doesn't so what can I say. I am not giving up I think I just messed up. I am mad at myself and thats the whole story and I am sticking to it.
Waiting for my next moive Bob 
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cazman
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #8 on: Jun 19th, 2005, 4:14pm » |
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thats great jokrs2 i happy for you i hope it continuse to work for you im gonne do the morning glory gig again tomarrow was gonna today but its not gonna happen to many family members around to deal with keep us updated on how things go
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Candycane
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #9 on: Jun 20th, 2005, 4:44pm » |
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on Jun 19th, 2005, 4:21pm, jokrs2 wrote:| Yes. A great fathers day to say the least. Laid out in the sun for a while and listened to some music. I am completely pain free. Happy fathers day to all you other dad's out there. Blessings, Joe |
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Glad you had a good Fathers Day....thanks for your help this weekend with my melt down..I think my cycle has broke. Putting on my bikini now too! YIPEE!!!!
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Bob P
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #10 on: Jun 20th, 2005, 5:17pm » |
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On the issue of Trex. It has a 1/2 life elimination rate of 2 hours. Therefore:
t+2 hrs = 1/2 dose
t+4 hrs = 1/4 dose
t+6 hrs = 1/8 dose
t+8 hrs = 1/16 dose
t+10 hrs = 1/32 dose
t+12 hrs = 1/64 dose
You could pretty much say that trex is out of your system in 12-14 hours.
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Mrs. Barlow, I never, and I repeat never, ever pissed in your steam iron.
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Pinkfloyd
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #11 on: Jun 20th, 2005, 5:51pm » |
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on Jun 20th, 2005, 5:17pm, Bob P wrote:| You could pretty much say that trex is out of your system in 12-14 hours. |
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And your point is? Or is this just for informational purposes?
Are you saying you have some proof that after it leaves the system, it leaves no longer lasting effects in its wake? If so, I'd be happy to add it to our database of information.
You could say we're pretty much out of Afghanistan.
Bobw
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Bob P
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #12 on: Jun 20th, 2005, 6:09pm » |
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LOL
Should have known.
You can add the above post of mine to your database. It's fact.
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Mrs. Barlow, I never, and I repeat never, ever pissed in your steam iron.
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Jonny
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #13 on: Jun 20th, 2005, 6:12pm » |
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on Jun 20th, 2005, 6:09pm, Bob P wrote:| You can add the above post of mine to your database. It's fact. |
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Smarty Pants
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Ueli
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #14 on: Jun 20th, 2005, 6:23pm » |
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on Jun 20th, 2005, 5:17pm, Bob P wrote:| You could pretty much say that trex is out of your system in 12-14 hours. |
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Could be, but I'm not entirely sure about that. Your calculation holds for the Imitrex circulating in the blood stream, but we are interested in the Imitrex bound to the 5HT receptors. Only if the binding time to the receptors is short (minutes or less) we will have a dynamic equilibrium and the amount docked to the receptors is proportional to the serum concentration. I think this needs some further investigations.
Ueli 
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Bob P
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #15 on: Jun 20th, 2005, 6:23pm » |
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Well crud. Using his logic, how do we know that farting into the wind on Tuesday doesn't negate the effects of all psycadhelics for 93 1/2 hours? Ya put the numbers in front of them and they still can't accept it.
Ueli - if it remained bound to the 5HT receptors we wouldn't get hit again 4 hours after shooting up.
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| « Last Edit: Jun 20th, 2005, 6:25pm by Bob P » |
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Mrs. Barlow, I never, and I repeat never, ever pissed in your steam iron.
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rextangle
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #16 on: Jun 20th, 2005, 6:53pm » |
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Hey BobP,
It's spelled PSYCHEDELIC!!! Not "psycadhelics"... if you're gonna try to be a smart ass, learn to spell first!!!!!
-From a foreigner... or do you spell it FURIGNER???
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Bob P
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #17 on: Jun 20th, 2005, 7:13pm » |
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Hey Rex,
Personally I don't a rat's ass how it's spelled.
Glad the melatonin is working for you.
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Mrs. Barlow, I never, and I repeat never, ever pissed in your steam iron.
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Pinkfloyd
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #18 on: Jun 20th, 2005, 8:32pm » |
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on Jun 20th, 2005, 6:09pm, Bob P wrote:LOL
Should have known.
You can add the above post of mine to your database. It's fact. |
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Some is and some of it is your theory.
I should have known you wouldn't answer any of my questions, you never do.
Half-life pertains to both/either elimination or matabolization. If you know how long all the different matabolites of the various triptans remain active, you still need to know how long the effects are for up and down regulation of the receptors.
How does Imitrex increase cluster activity and length of cycles, according to your half-life theory? Or are the current theories based upon clinical trials by researchers on this subject, incorrect and you are right? Maybe you should contact them and set them straight.
Feel free to explain how psilocybin stops clusters past your half life theory. Maybe you still don't believe it does.
Bobw
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Bob P
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #19 on: Jun 21st, 2005, 9:42am » |
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It's not "my theory". It's in all the medical literature.
Quote:| Pharmacokinetic parameters following a 6-mg subcutaneous injection into the deltoid area of the arm in 9 males (mean age, 33 years; mean weight, 77 kg) were systemic clearance: 1,194 ± 149 mL/min (mean ± S.D.), distribution half-life: 15 ± 2 minutes, terminal half-life: 115 ± 19 minutes, and volume of distribution central compartment: 50 ± 8 liters. Of this dose, 22% ± 4% was excreted in the urine as unchanged sumatriptan and 38% ± 7% as the indole acetic acid metabolite. |
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Terminal half life 115 minutes.
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Mrs. Barlow, I never, and I repeat never, ever pissed in your steam iron.
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Flash
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #20 on: Jun 21st, 2005, 10:44am » |
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If I pour boiling water on my hand the half life of the water being at boiling point is about 0.5secs. The water then quickly cools over a period of a few seconds down to room temp and within a few minutes all traces of the water have disappeared from my hand.
The burn lingers around for much longer.
The same thing would be true of concentrated acid (I mean hydrocholic etc as opposed to LSD )
If I take a largish quantity of aspirin then the lining of my stomach becomes damaged, and this damage extends beyond the time the aspirin is in my system.
If I drink alcohol then my liver ensymes remain elevate beyond the time it takes for the alcohol to leave my system.
It's naive to think of something as just passing through the body. Only very inert materials go in one hole and one the other LOL. Most everything else is metabolised in some way thus becoming something else. The effects of a substance can extend beyond the time it takes to become fully metabolised. By effects I would include the time it takes for the physiological system to return to it's baseline.
This is a good example of why certain people shouldn't read scientific papers then start spouting a load of bullshit based on their personal interpretation of those scientific findings. Also note that findings are not necessarily facts.
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Pinkfloyd
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #21 on: Jun 21st, 2005, 10:52am » |
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on Jun 21st, 2005, 9:42am, Bob P wrote:It's not "my theory". It's in all the medical literature.
Terminal half life 115 minutes. |
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I wasn't speaking about half life values being your theory. But nice try.
Still haven't answered any of my questions.
Bobw
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Bob P
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #22 on: Jun 21st, 2005, 11:11am » |
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Quote:| This is a good example of why certain people shouldn't read scientific papers |
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and why some people who don't read scientific papers should.
The whole point is candy was using trex. People (Nani, Langa) were asking about the trex interfering with the seeds. I shared the half life of trex to show that it is out of your system in a fairly short time. Probably why they say don't mix triptans within a 24 hour period and not within a 5 day period.
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Mrs. Barlow, I never, and I repeat never, ever pissed in your steam iron.
"SHUT UP HUB!"
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Pinkfloyd
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #23 on: Jun 21st, 2005, 1:11pm » |
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on Jun 21st, 2005, 11:11am, Bob P wrote:
Probably why they say don't mix triptans within a 24 hour period and not within a 5 day period. |
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It could also be a concern more about plasma levels and the adverse effects it could have on the heart, but then what would I know.
I'd know more if you'd answer my questions.
It's obvious (if you look at the publications and listen to the people here that use it) that Imitrex changes the cluster intensities and frequencies, long after this 24 hour period. More to the extent of the length of the remaining cyle duration. And, it's not a change for the better. How many people here have reported an adverse long term effect vs. a positive long term effect, attributable to Imitrex use?
You can believe this or not, your choice, but almost everyone that stops using Imitrex to begin getting ready for a psilocybin dose, reports the clusters begin getting better over this 5 day period, not just over the first 24 hours. There is more to it than half lives.
Bobw
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"Nothing is so firmly believed as what we least know."
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Bob P
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Re: Rivea Corymbosa (LSA) Tonights Test
« Reply #24 on: Jun 21st, 2005, 1:48pm » |
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In this case it seems that Candycanes attacks were getting worse without trex which caused her to go to the trex.
My attacks get more frequent when I use trex but return to normal pattern by the next day when I stop using it.
Again, the only point was to let CC know that she is "detoxed" from trex within 24 hrs. according to those who have actually done some research and are not just throwing out guesses.
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Mrs. Barlow, I never, and I repeat never, ever pissed in your steam iron.
"SHUT UP HUB!"
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