Author |
Topic: Imitrex--may change cluster pattern (Read 318 times) |
|
Bob_Johnson
New Board Hall of Famer
Gender: 
Posts: 1796
|
 |
Imitrex--may change cluster pattern
« on: Aug 23rd, 2004, 6:44am » |
 Quote  Modify
|
Headache. 2004 Jul;44(7):713-8.
Subcutaneous sumatriptan induces changes in frequency pattern in cluster headache patients.
Rossi P, Lorenzo GD, Formisano R, Buzzi MG.
Objectives.-To document the relationship between the use of subcutaneous (SQ) sumatriptan (sum) and a change in frequency pattern of cluster headache (CH) in six patients. To discuss the clinical and pathophysiological implications of this observation in the context of available literature. Background.-Treatment with SQ sum may cause an increase in attack frequency of CH but data from literature are scant and controversial. Methods.-Six CH sum-naive patients (three episodic and three chronic according to the International Headache Society (IHS) criteria) are described. Results.-All six patients had very fast relief from pain and accompanying symptoms from the drug but they developed an increase in attack frequency soon after using SQ sum. In all patients, the CH returned to its usual frequency within a few days after SQ sum was withdrawn or replaced with other drugs. Five patients were not taking any prophylactic treatment and SQ sum was the only drug prescribed to treat their headache. Conclusions.-Physicians should recognize the possibility that treatment of CH with SQ sum may be associated with an increased frequency of headache attacks.
PMID: 15209695 [PubMed - in process]
|
|
 IP Logged |
Bob Johnson
|
|
|
pubgirl
Guest
|
|
Re: Imitrex--may change cluster pattern
« Reply #1 on: Aug 23rd, 2004, 7:22am » |
Quote Modify
 Remove
|
when PG was asked if Imigran and 02 can make CH attacks more frequent, his reply to both was affirmative.
Also when asked if Verap could prolong cycles, the answer is "probably"
Depressing thought that we still don't even have a really effective treatment prescribable by GP's, never mind a cure.
Fed up now 
W
|
|
IP Logged |
|
|
|
DerbyDemon
New Board Newbie
Pardon me. Is that a dagger in my head?
Gender:
Posts: 30
|
|
Re: Imitrex--may change cluster pattern
« Reply #2 on: Aug 23rd, 2004, 7:28am » |
Quote Modify
|
And to think I've been sticking myself with the stuff like a junkie all summer.
|
|
IP Logged |
|
|
|
pubgirl
Guest
|
|
Re: Imitrex--may change cluster pattern
« Reply #3 on: Aug 23rd, 2004, 7:59am » |
Quote Modify
Remove
|
Do we really have any choice as Imitrex and 02 are the the best abortives we have?
|
|
IP Logged |
|
|
|
manana
New Board Junior
I love YaBB 1G - SP1!
Gender:
Posts: 71
|
|
Re: Imitrex--may change cluster pattern
« Reply #4 on: Aug 23rd, 2004, 8:50am » |
Quote Modify
|
Why not inform the insurance companies & Pharmacuticals so that more doses can be approved for the ones who need to use triptans?
|
|
IP Logged |
|
|
|
IndianaJohn
New Board Hall of Famer
Into the jaws of the Beast we ride!
Gender:
Posts: 643
|
|
Re: Imitrex--may change cluster pattern
« Reply #5 on: Aug 23rd, 2004, 8:58am » |
Quote Modify
|
That sounds like a double edged sword. The more you use the more individual HA's you'll get. I think it's true of the nasal sprays too. So once again we need to limit ourselves when possible to avoid prolonging a cycle....
CH just sucks!!!...
|
|
IP Logged |
Did my brains fall out or is this headache over?
|
|
|
|
|
|
Home
Help
Search
Members
Member Map
Login
Register
Reply
Notify of replies
Send Topic
Print
test rss