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   Author  Topic: Please help.  Verapamil question.  (Read 241 times)
eyes_afire
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Please help.  Verapamil question.
« on: May 24th, 2004, 6:01pm »
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Hi folks.  I find myself in a strange situation.  Please understand that I'm not asking for medical advice, but rather for information and personal experience.
 
Background:  My neuro's office seems to be undergoing a bit of reorganization and incidentally my CH's are worsening and maybe verapamil is failing a bit as evidenced by my 2am skullcrushing.  I requested to increase my verapamil SR to 360 mg.  Unfortunately, I've had to converse with the ubiquitous 'physicians assistant'.  Anyhow, he authorized the prescription for verapamil immediate release which I have never taken before.  I questioned it (thinking it was a mistake), but it seems that the office believes that the immediate release is more appropriate for CH.  Of course, I'm very glad to see that the doc is up-to-date on CH treatments and I can see many advantages to using the immediate release formulation.  But...
 
I think I read on this message board that SR should be tapered before starting immediate release due to safety concerns (but I'm not sure).  'Physicians assistant' thinks I can just change over without taper because my current dose isn't that large.
 
Question:  Does anyone have information that changing formulations without tapering would be risky?  For those who have changed formulations, did you taper first?
 
thanks in advance
 
--- Steve
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kissmyglass
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Re: Please help.  Verapamil question.
« Reply #1 on: May 24th, 2004, 6:33pm »
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Hi Steve,
  I think it's the SR that we need.  Think you need to taper off it to quit, not sure about switching over....
 
Kev
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Ueli
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Re: Please help.  Verapamil question.
« Reply #2 on: May 24th, 2004, 7:16pm »
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Hi eyes,
 
Verapamil SR takes about 6 hours until a tablet is fully resorbed. So, if you would change over without a break, there would be a short (~1 day) peak. If you have no heart and BP problems this is probably of no consequence, especially as you are on a rather low dose of the RS version.  
If you end the RS with half the dose for one day and then start the regular the next day with a half dose too, you will probably be on the safe side.
(Recently Roxy changed from a too low dose extended to a too low dose of regularand and had some remarkable side effects: No CH attacks for a week.)  
 
All about the different versions of Verapamil on rxlist.com
 
Good luck,
Ueli
 
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Re: Please help.  Verapamil question.
« Reply #3 on: May 24th, 2004, 7:46pm »
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Hey Steve...Ueli's post above?  Thats really what I meant to say the first time... Grin Grin
 
Kev
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