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   Intranasal Capsaicin Safe Long Term?
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   Author  Topic: Intranasal Capsaicin Safe Long Term?  (Read 226 times)
BILLY
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Intranasal Capsaicin Safe Long Term?
« on: Mar 29th, 2003, 6:42pm »
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Hi all I know capsaicin is widely used on the skin & is considered safe even for long term indefinite use on the skin but was curious if it is just as safe intranasally?  I know it will burn much more as the mucous membranes are much more sensitive but will it damage the nasal mucosa like cocaine can for example?
 
I searched the site & noticed one user from Israel has success with intranasal capsaicin without mentioning any damage but noticed one poster warned of this??
 
Anyone know?  If there is a response without any noticeable lasting side effects, is there reason to be concerned that there may be in the long run?  
 
I understand it depletes the nerves locally of pain & vasodilating transmitters (substance P & CGRP) & acts like a local calcium channel blocker but the literature does not indicate any long term studies.  I think 4 one week treatments in 2 years is the longest study & did not indicate adverse effects...
 
Would appreciate any insight.
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Bob_Johnson
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Re: Intranasal Capsaicin Safe Long Term?
« Reply #1 on: Mar 30th, 2003, 8:18am »
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I've never seen any med literature with warnings about side-effects. Suspect this is because there is still too little experience with long-term use.
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Bob Johnson
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