Author |
Topic: Migraine drug with antidepressants may harm: FDA (Read 609 times) |
|
Melissa
Guest
|
 |
Migraine drug with antidepressants may harm: FDA
« on: Jul 19th, 2006, 3:36pm » |
 Quote  Modify
 Remove
|
From Reuters....
Migraine drug with antidepressants may harm: FDA
1 hour, 10 minutes ago
The use of some migraine drugs with certain antidepressants can cause a fatal condition in which patients experience hallucinations, overactive reflexes and rapid heart beat, the U.S. Food and Drug Administration warned on Wednesday.
The antidepressants of concern include selective serotonin reuptake inhibitors and selective serotonin/norepinephrine reuptake inhibitors, the FDA said.
Patients should talk to their doctors before discontinuing antidepressant or migraine drugs known as triptans, it added.
Does anyone have anything else to expand on this??
Thanks,
mel
|
| « Last Edit: Jul 19th, 2006, 5:10pm by Melissa » |
 IP Logged |
|
|
|
walkertexasranger
New Board Newbie
Gender: 
Posts: 30
|
 |
Re: Migraine drug with antidepressants may harm: F
« Reply #1 on: Jul 19th, 2006, 9:21pm » |
Quote Modify
|
And these drugs are called??????
|
|
IP Logged |
|
|
|
clarence
CH.com Alumnus
New Board Hall of Famer
Wake up
Gender:
Posts: 1020
|
|
Re: Migraine drug with antidepressants may harm: F
« Reply #3 on: Jul 20th, 2006, 7:38am » |
Quote Modify
|
I saw this too...you beat me to it!
I take Imitrex and Prozac...and I will probably mention it to my doc on Tuesday when see him.
Casey
edit to add: the article says that these drugs are:
Quote:| Commonly prescribed SSRIs include Prozac, Zoloft, Paxil and Lexapro. SNRIs include Cymbalta and Effexor. Triptans include Amerge, Axert, Imitrex and Zomig. |
|
|
| « Last Edit: Jul 20th, 2006, 7:39am by clarence » |
IP Logged |
NY Yankees Suck!!!
"Bart, don't make fun of Grad students. They just made a terrible life decision," Marge Simpson
Where I live: http://rainfallsoneveryone.com
|
|
|
Melissa
Guest
|
|
Re: Migraine drug with antidepressants may harm: F
« Reply #4 on: Jul 20th, 2006, 10:15am » |
Quote Modify
Remove
|
Thank you John and Casey.
On a more personal note, I was on Cymbalta for my last cycle, but fortunately I did not need the imitrex I had stashed because I was trying kudzu along with O2. I am currently on nothing (except vitamins) and out of cycle.
This whole thing has me EXTREMELY concerned about everyone here as a huge majority of us are on SSRI/SSRNI's along with taking triptans.
Please, everyone carefully monitor your physical and mental health!!
Melissa
|
|
IP Logged |
|
|
|
thomas
CH.com Alumnus
New Board Hall of Famer
"Hit like a phillips head into my brain."
Gender:
Posts: 3281
|
|
Re: Migraine drug with antidepressants may harm: F
« Reply #5 on: Jul 20th, 2006, 3:53pm » |
Quote Modify
|
Triptans are chemically very similar to seretonin. I am going to have to re-think my own treatment regimen.
|
|
IP Logged |
Religion and sex are powerplays. Manipulate the people for the money they pay. Selling skin, selling God, the numbers look the same on their credit cards. Triptans cause rebounds. Learn it, believe it, live it. I use triptans as the absolute LAST RESORT when treating my CH.
|
|
|
Pinkfloyd
New Board Hall of Famer
comfortably numb
 
Gender:
Posts: 1406
|
|
Re: Migraine drug with antidepressants may harm: F
« Reply #6 on: Jul 20th, 2006, 7:27pm » |
Quote Modify
|
Many migrainers have known about this for a long time. Unfortunately, its usually the sufferers that begin logging bad side effects before the FDA gets involved and does a study.
Serotonin Syndrome can be very serious/dangerous and if allowed to go on for too long, becomes more difficult to treat, and recover. Its a good idea for anyone using SSRI's and/or MAOIs and triptans to know what the symptoms are.
It isn't something that happens often but the numbers of cases have been on the rise.
Since SSRI's aren't usually very effective for treating clusters, I don't think many doctors/researchers have looked at these possible complications for cluster sufferers as often as with migraines, since many migrainers use SSRI's, MAOIs and now, in combination with the triptans, in one treatment plan for migraines.
They seem to forget, or they may be being prescribed by two different doctors, for problems unrelated to cluster treatments, that many cluster folks DO use these combos.
Check out the symptoms and don't wait around if they begin to appear. Here's a good place to start:
http://www.uspharmacist.com/oldformat.asp?url=newlook/files/feat/acf2fa6 .htm
Bobw
|
|
IP Logged |
"Nothing is so firmly believed as what we least know."
"There is no passion so contagious as that of fear."
[Michel de Montaigne
www.clusterbusters.com
www.obscuredview.blogspot.com
|
|
|
MattNL
New Board Newbie
I love YaBB 1G - SP1!
Posts: 4
|
|
Re: Migraine drug with antidepressants may harm: F
« Reply #7 on: Jul 21st, 2006, 3:37am » |
Quote Modify
|
I suspected this already. Have used several years ago SSRI combined with sumatriptan and thought it had very negative impact on CH. (more attacks, more intense) My Neuro told me (6 years ago!) he heard this from more patients.
BTW I also found something interesting on the internet.
I think good news specially for Americans?
I hope generic Sumatriptan subcutane will also soon be available here in Holland because of cost.
http://www.spectrumpharm.com/sumatriptan.html
Regards,
|
|
IP Logged |
|
|
|
FramCire
CH.com Alumnus
New Board Hall of Famer
Life like a froward child must be humored a little
Gender:
Posts: 847
|
|
Re: Migraine drug with antidepressants may harm: F
« Reply #8 on: Jul 22nd, 2006, 6:47pm » |
Quote Modify
|
Thank you for posting this. I just started Lexapro TODAY and took it minutes after taking Maxalt.
I will have to talk tomy doctor about it. I was on Wellbutrin but the 3 times I tried taking it, it triggered a cluster. The first 2 times I attributed to coincidence, not this time.
|
|
IP Logged |
You've overstayed your welcome since the day we met but it doesn't seem to matter to you. No medications are your master, nothing makes you fret, it's a helpless feeling having nothing I can do
|
|
|
Melissa
Guest
|
|
Re: Migraine drug with antidepressants may harm: F
« Reply #9 on: Jul 28th, 2006, 8:49pm » |
Quote Modify
Remove
|
bump
|
|
IP Logged |
|
|
|
big guy
New Board Junior
Gender:
Posts: 99
|
|
Re: Migraine drug with antidepressants may harm: F
« Reply #10 on: Aug 9th, 2006, 7:12am » |
Quote Modify
|
This needs to be kept recent. An E R Dr prescribed Axert for me with out seeing I was on Celexa. Or maybe he didn't know, but after the third time I took the Axert I began to feel really bad. Fever, chills, profuse sweating, confusion and alternating between lethargic and almost manic. I found this thread and recognised seratonin syndrome. Since my regular Dr was out of town I decided to quit the Celexa on my own. My Dr is very agreeable to letting me work with my meds as he has beeen very impressed with the research I have done, mostly through links on this site. What a great resource CH.com is. I went to see the Dr when he returned to town, and showed him the information. My diagnosis and treatment were right on. He is adjusting all my medications based on information I have provided him.
Thanks to everyone here for a great resource
Big guy
|
|
IP Logged |
|
|
|
|
|
|
Home
Help
Search
Members
Member Map
Login
Register
Reply
Notify of replies
Send Topic
Print
test rss