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Mattrf
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Upping Verapamil?
« on: Apr 28th, 2006, 3:03pm »
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My doctor upped me to 360 of Verapamil per day, my question is should I take it all at once or take it 120 at a time three times a day?
The nurse told me to split it up but I remember the doc saying it didn’t matter.
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Re: Upping Verapamil?
« Reply #1 on: Apr 28th, 2006, 4:36pm »
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Are you taking the regular release or sustained release?  The current theory is that the regular release works better.  
 
I can't say what is the best for you.  Since your doctor was ambivalent about it, ask your pharmacist.
 
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Bob P
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Re: Upping Verapamil?
« Reply #2 on: Apr 28th, 2006, 5:29pm »
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Verapamil:  
 
Perhaps the most effective calcium channel blocker for prophylaxis of CH.  
 
The recommended dose is 80-120 mg (immediate release), 3-4 times a day.  
 
Side effects include constipation and water retention.  
 
Patients intolerant to verapamil should be tried on nimodipine, diltiazem or nifedipine.
 
 
I space mine out throughout the day.  It doesn't even start to have an effect on frequency/intensity until 480mg / day for me.
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Re: Upping Verapamil?
« Reply #3 on: Apr 29th, 2006, 11:11am »
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I'm on 480 mg/day, and I divvy it up 240 twice a day.
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Re: Upping Verapamil?
« Reply #4 on: Apr 30th, 2006, 12:06am »
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I take 240mgs twice a day.  Ask yourself this.  What time of the day do you get hit more than others.  If you get hit at night more take the larger dose at night if it is in the day time take it in the daytime.
 
I hope this helps.
 
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Re: Upping Verapamil?
« Reply #5 on: Apr 30th, 2006, 3:55am »
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Its a prevenative....just split it!
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Re: Upping Verapamil?
« Reply #6 on: Apr 30th, 2006, 8:13am »
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I've always believed that verapamil maintains a pretty even level in the bloodstream regardless of how you space it out over the course of the day. That's why it takes a week or so to start working once you start taking it. Whenever I go back on it after a headache-free period, I often have to take a prednisone taper until it ramps up in my system and starts becoming effective. Same with lithium. FWIW.
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