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rcw
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I am a female cluster sufferer for a number if years, and am about to get married this september, and was wondering if anyone has had any experience with pregnancies and clusters and I would really love to have a baby but am scared to death about going off my medication. Any information is greatly appreciated.
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Bob_Johnson
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Re: pregnancy
« Reply #1 on: Apr 26th, 2006, 2:10pm » |
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Re. special needs of women. Both of these in HEADACHE QUARTERLY, Vol X, #2, 1991: "Women and headaches:a comprehensive approach", p. 31-36. "Special considerations in the management of headache in women", p. 37-43. The last one focuses on role of hormones in headache and how medications must be altered.
Take these citations to your library and they can get you copies.
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Re: Clusters and Pregnancy
« Reply #1 on: Oct 29th, 2004, 8:37am » Quote Modify Remove
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Issues about med effects are sufficiently complex and fluid that I would work closely with your ob doc and, ideally, with a headache specialist (acting as a consultant).
Given where you are in your pregnancy, you might print out this message and show to your doc.
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CNS Drugs. 2003;17(1):1-7. Related Articles, Links
Safety of sumatriptan in pregnancy: a review of the data so far.
Loder E.
Harvard Medical School, Boston, Massachusetts, USA. eloder@partners.org
The high prevalence of migraine in women during their reproductive years means that new drug treatments for migraine, such as the serotonin 5-HT(1B/1D) receptor agonists (the 'triptans'), are likely to be widely used by women of childbearing potential. Scrutiny of these agents in an effort to detect any signal of teratogenicity is thus important. A systematic review of the medical literature was conducted to identify information regarding the safety of sumatriptan during pregnancy. This agent was chosen to be investigated because it has been available for the longest and is the most widely used of the triptan class. Information was obtained regarding the impact of migraine on pregnancy outcome, and data on sumatriptan use in pregnancy were obtained from animal studies, preclinical drug trials, postmarketing surveillance efforts, prospective pregnancy registries, national birth registries and teratogen information services. Synthesis of information from these sources is sufficient to rule out a large increase in birth defects from sumatriptan use during pregnancy and is reassuring for cases where inadvertent exposure to sumatriptan during pregnancy has occurred. However, current information is not sufficient to rule out small increases in the risk for birth defects. For this reason, caution should be exercised in making a positive recommendation for the use of sumatriptan during pregnancy.
Publication Types:
Review
Review, Tutorial
PMID: 12467489 [PubMed - indexed for MEDLINE]
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I checked drug info on medscape.com and it's o.k. for limited use in pregnancy.
1: Headache 2001 Sep;41(:813-6
Olanzapine as an Abortive Agent for Cluster Headache.
Rozen TD.
Department of Neurology, Jefferson Headache Center/Thomas Jefferson University Hospital, Philadelphia, Pa.
OBJECTIVE: To evaluate olanzapine as a cluster headache abortive agent in an open-label trial. BACKGROUND: Cluster headache is the most painful headache syndrome known. There are very few recognized abortive therapies for cluster headache and fewer for patients who have contraindications to vasoconstrictive drugs. METHODS: Olanzapine was given as an abortive agent to five patients with cluster headache in an open-label trial. The initial olanzapine dose was 5 mg, and the dose was increased to 10 mg if there was no pain relief. The dosage was decreased to 2.5 mg if the 5-mg dose was effective but caused adverse effects. To be included in the study, each patient had to treat at least two attacks with either an effective dose or the highest tolerated dose. RESULTS: Five patients completed the investigation (four men, one woman; four with chronic cluster, one with episodic cluster). Olanzapine reduced cluster pain by at least 80% in four of five patients, and two patients became headache-free after taking the drug. Olanzapine typically alleviated pain within 20 minutes after oral dosing and treatment response was consistent across multiple treated attacks. The only adverse event was sleepiness. CONCLUSIONS: Olanzapine appears to be a good abortive agent for cluster headache. It alleviates pain quickly and has a consistent response across multiple treated attacks. It appears to work in both episodic and chronic cluster headache.
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Olanzapine has a brand name of "Zyprexa" and is a antipsychotic. Don't be put off by this primary usage. Several of the drugs used to treat CH are cross over applications, that is, drugs approved by the FDA for one purpose which are found to be effective with unrelated conditions--BJ.
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OTC meds are not very helpful with cluster, as you know, but may be one of the few options available to you. Some folks have good luch aborting/easing an attack by applying an ice pack to the pain site. Others find very hot water also works; others have used a hair dryer blasting the pain site works! No predicting; just try.
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Bob Johnson
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lionsound
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breathe
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Re: pregnancy
« Reply #2 on: Apr 28th, 2006, 10:12am » |
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do not let CH keep you from living you life!
go here:
http://www.ouch-us.org/newsletters/newsletters.shtml
click on the April OUCH newsletter and scroll down. A very interesting interview article on pregnancy and CH. (i'm in it  )
the key is a good OB, a good HA specialist and a fantastic support system.
Feel free to send me a PM if you have any questions or want to chat more about it.
Be well and PF!
-Rori
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Tara Ann
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Re: pregnancy
« Reply #3 on: May 3rd, 2006, 1:21pm » |
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Personally I was HA free during pregnancy. Other than those run of the mill tension HA.......definately can't complain about those  COngrats and like said above don't let CH stop you from living, if u want babies then just do it 
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mandyshane1
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Re: pregnancy
« Reply #4 on: May 3rd, 2006, 10:46pm » |
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I was PF for my first preganancy 7 years ago. I had a baby last June, thought I was smart and tried to plan my pregnancy around my CH cycle ( usually got hit in late July- Sept) . Well, that jumped up and bit me! Got a full blown 6 week cycle in November ( 2nd trimester) . Neuro and OB worked together, used O2, and Pred, and my baby boy came out just fine. I can't lie, was a rough 6 weeks, worrying about side effects of pred on baby, and O2 doesn't work well in the middle of the cycle for me when the CH's are kip 10, but he came out just fine and the sacrafice was well worth it. You can't let the CH's run your life. I say go for it.
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mzrolwes
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Re: pregnancy
« Reply #5 on: Jun 9th, 2006, 3:51pm » |
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I was pregnant inbetween episodes but I can relate. As I am plunging head first into a cluster and have to quit ttc. I don't know how frequent your cycles are but maybe you can plan conception between them.
Migraines aren't the same but mine went away for the majority of my pregnancy. I had one in the 1st trimester and as I'm sure you know tylenol does NOTHING. I did have many headaches towards the end as a side effect of drugs they give you to stop labor (I went into to preterm labor) and then in the hospital afterwards. All I can say is benedryl in an IV is a beautiful thing. Even though the pain is there, thoughts of your baby help you thru.
Best of luck for a pain free pregnancy.
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Marcella
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