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hurtinunit
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Hypothalmus Question
« on: Jun 16th, 2005, 2:38pm »
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ok ive been doing my reading about all the research that clusterheads have abnormal hypothalmythings
im just wondering if anyone can translate this into english also if this is true and i dont doubt it how can you go into remission if the hypothalmy is still messed up and why does it start when it does i know your not doctors or anything just wondering mine didnt start till i was 33 cant think of anything that changed in my life smoke pack a day havent drank in a long time never drank much was my hypothalmus in hibernation all this time Roll Eyes
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hurtinunit
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Re: Hypothalmus Question
« Reply #1 on: Jun 16th, 2005, 2:40pm »
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oops posted twice Tongue Tongue
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Bob P
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Re: Hypothalmus Question
« Reply #2 on: Jun 16th, 2005, 4:19pm »
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Well they know that the hypothingy in clusterheads has an extra little bundle of nerve fibers on the back of it that normal heads don't have.
 
They know that when a cluster starts, the hypothingy in a cluster head activates.  When you induce other kinds of head pain on a clusterheads head, the hypothingy doesn't activate.
 
Why does it do what it does?  They don't know!
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Re: Hypothalmus Question
« Reply #3 on: Jun 16th, 2005, 4:26pm »
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If you click on "Remove" in your other post before some replies to it, it will be removed. Grin
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Redd
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Re: Hypothalmus Question
« Reply #4 on: Jun 16th, 2005, 4:31pm »
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The hypothalamus also is the body's inner clock.  It regulates the body and brain in the dialy sleep/wake pattern, weekly and seasonal cycles. Hence the clockwork pattern of attacks when in cycle, and regularity of the cycles themselves.  One discription of the abnormality is as BobP states, the extra nerve bundle.  Another is that the existing cells in the inferior posterior hypothalamus are more dense and compact than in the normal hypothalamus.  Either way, they are simply not normal cell/nerve structures back there. By what mechanism this effects the vascular and trigeminal changes during an attack is not known.  
 
I hope Bob and I were able to make it all as clear as mud for you.... Smiley
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Re: Hypothalmus Question
« Reply #5 on: Jun 16th, 2005, 5:09pm »
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on Jun 16th, 2005, 4:19pm, Bob P wrote:
Well they know that the hypothingy in clusterheads has an extra little bundle of nerve fibers on the back of it that normal heads don't have.

 
Bob, I'm new here but I respectfully disagree. Grin
 
The group of people gathered here care about each other, are willing to help each other, provide support, advice, love, etc. For the most part, "normal" people don't do that as much as this group does.
 
I think that extra hypothalingy is what makes us normal, the rest of the world shoudl be as "normal" as us! laugh
 
Jose
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burnt-toast
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Re: Hypothalmus Question
« Reply #6 on: Jun 16th, 2005, 5:21pm »
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Abnormal function of the hypothalamus
Cluster attacks typically occur with clock-like regularity during a 24-hour day. The cycle of cluster periods often follow the seasons of the year. These patterns suggest that the body's biological clock is involved. In humans, the biological clock is located in the hypothalamus, which lies deep in the center of the brain. Among the many functions of the hypothalamus is control of the sleep-wake cycle and other internal rhythms.
 
Abnormalities of the hypothalamus may explain the timing and cyclical nature of cluster headache. Studies have detected increased activity in the hypothalamus during the course of a cluster headache. This activity isn't seen in people with other headaches such as migraine.
 
Studies also indicate that people have abnormal levels of certain hormones, including melatonin and testosterone, during cluster periods. These hormonal changes are believed to be due to a problem with the hypothalamus. Other studies reveal that participants with cluster headache have a larger hypothalamus, compared with that of participants who don't have this headache. But it remains unknown what causes these abnormalities in the first place.
 
In the anatomy of mammals, the hypothalamus is a region of the brain located below the thalamus, forming the major portion of the ventral region of the diencephalon and functioning to regulate certain metabolic processes and other autonomic activities. The hypothalamus links the nervous system to the endocrine system by synthesizing and secreting neurohormones often called releasing hormones because they function by stimulating the secretion of hormones from the anterior pituitary gland — among them, gonadotropin-releasing hormone (GnRH). The neurons that secrete GnRH are linked to the limbic system, which is very involved in the control of emotions and sexual activity. The hypothalamus is also the area of the brain that controls body temperature, hunger and thirst, and circadian (biological clock) cycles. Quote:

 
In short it's a major link between our bodies electrical, chemical and regualtory systems and as we all know all too well should be given much respect. bow
 
All hail the Hypothalamus! bow  
 
 
Tom    
 
 
 
 
 
« Last Edit: Jun 16th, 2005, 5:25pm by burnt-toast » IP Logged

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Re: Hypothalmus Question
« Reply #7 on: Jun 17th, 2005, 8:11pm »
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on Jun 16th, 2005, 5:21pm, burnt-toast wrote:

 
All hail the Hypothalamus! bow  
 
Tom    
 

 
Funny Tom  Grin
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yikes-another-one
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Re: Hypothalmus Question
« Reply #8 on: Jun 17th, 2005, 8:30pm »
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so another good question would be why the triptans work for a while and then suddenly stop being effective
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Re: Hypothalmus Question
« Reply #9 on: Jun 17th, 2005, 11:04pm »
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on Jun 17th, 2005, 8:30pm, yikes-another-one wrote:
so another good question would be why the triptans work for a while and then suddenly stop being effective

 
The question could be expanded to include just about every medication and treatment.  From what I've been reading effectiveness changes from cycle to cycle and even week to week.  It could stem from the fact that most meds. we get were developed to treat other illnesses.  
 
The good news is that 10 years ago I found almost nothing when researching CH.  Tooday I  find loads of useful information.  Although improving, the unknowns associated with this disease are still many and specific answers few.  
 
Tom  
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